Previously published B/B(A) subgroup alleles and the 7 novel B subgroup alleles reported here
| Allele description . | Nucleotide change . | Amino acid change6-150 . | Individuals (families)6-151 . | Geographic origin6-152 . | Reference/GenBank accession no. . |
|---|---|---|---|---|---|
| B3-1 | 1054C>T | R352W | — | (United States) | B37 |
| Bel-1 | 641T>G | M214R | — | (Japan) | B10513 |
| Bel-2 | 669G>T | E223D | — | (Japan) | B10613 |
| Bw-1 | 871G>A | D291N | — | (Japan) | B10413 |
| ▸Bw-2 | 873C>G | D291E | 1 | France | AF324018 |
| ▸Bw-3 | 721C>T | R241W | 8 (2) | Sweden | AF324014 |
| ▸Bw-4 | 548A>G | D183G | 5 (2) | Sweden | AF324016 |
| ▸Bw-5 | 539G>A | R180H | 1 | United States | AF324015 |
| ▸Bw-6 | 1036A>G | K346E | 3 (1) | Finland | AF324019 |
| ▸Bw-7 | 1055G>A | R352Q | 2 (1) | United States | AF324020 |
| ▸Bw-8 | 863T>G | M288R | 1 | Turkey | AF324017 |
| B(A)-1 | 703A>G | S235G | 1 | Germany | 9 |
| B(A)-2 | 700C>G | P234A | — | (Asia) | 42 |
| Allele description . | Nucleotide change . | Amino acid change6-150 . | Individuals (families)6-151 . | Geographic origin6-152 . | Reference/GenBank accession no. . |
|---|---|---|---|---|---|
| B3-1 | 1054C>T | R352W | — | (United States) | B37 |
| Bel-1 | 641T>G | M214R | — | (Japan) | B10513 |
| Bel-2 | 669G>T | E223D | — | (Japan) | B10613 |
| Bw-1 | 871G>A | D291N | — | (Japan) | B10413 |
| ▸Bw-2 | 873C>G | D291E | 1 | France | AF324018 |
| ▸Bw-3 | 721C>T | R241W | 8 (2) | Sweden | AF324014 |
| ▸Bw-4 | 548A>G | D183G | 5 (2) | Sweden | AF324016 |
| ▸Bw-5 | 539G>A | R180H | 1 | United States | AF324015 |
| ▸Bw-6 | 1036A>G | K346E | 3 (1) | Finland | AF324019 |
| ▸Bw-7 | 1055G>A | R352Q | 2 (1) | United States | AF324020 |
| ▸Bw-8 | 863T>G | M288R | 1 | Turkey | AF324017 |
| B(A)-1 | 703A>G | S235G | 1 | Germany | 9 |
| B(A)-2 | 700C>G | P234A | — | (Asia) | 42 |
Nucleotide and amino acid changes are given in comparison to the consensus B allele.
▸ indicates novel B subgroup allele reported in this paper.
Charged residues involved in amino acid changes are shown in bold.
The number of samples identified by sequencing or PCR-ASP in this study is given for each allele (the number of apparently unrelated families investigated is given in parentheses).
Country from which the samples were referred (countries in parentheses refer to samples reported elsewhere).