Table 1. Polymorphic nucleotides... | American Society of Hematology

Table 1.

Polymorphic nucleotides detectable by restriction endonuclease digestion or sequence-specific primer PCR as used forABO genotyping in this study

Polymorphism detected by PCR-		Nucleotide position	Mutation	Alleles detectable^*	Allele reference	Method reference
RFLP	ASP	Nucleotide position	Mutation	Alleles detectable^*	Allele reference	Method reference
BstUI	−	188-189	GC → AT	O^1v	31	31
KpnI	−	261	G → −	O¹, O^1v, O¹ hybrids	6,32	19
HpaII	−	467	C → T	AsianA¹, A², O³, cis-AB, O¹-A² hybrid	8,32-35	19
NheI	+	526	C → G	B, O¹-B hybrids	6,32	14,36
MboI	−	646	T → A	A^x, A^x hybrids, O^1v	9,15,31	14
HpaII	−	703	G → A	B, O¹-B hybrids	6,32	19
DdeI	−	771	C → T	A^x hybrids,O^1v	31	15,31
—	+	796	C → A	B	6	36
—	+	802	G → A	O²	10	36
—	+	803	G → C	B	6	36
—	+	798-804	+G	A^el, O³	11,35	11
SalI	−	871	G → A	A³, B^x	7,13	14
—	+	1059-1061	−C	A², O³	34,35	14
HpaII	−	1096	G → A	B, O²	19	19

Polymorphism detected by PCR-		Nucleotide position	Mutation	Alleles detectable^*	Allele reference	Method reference
RFLP	ASP	Nucleotide position	Mutation	Alleles detectable^*	Allele reference	Method reference
BstUI	−	188-189	GC → AT	O^1v	31	31
KpnI	−	261	G → −	O¹, O^1v, O¹ hybrids	6,32	19
HpaII	−	467	C → T	AsianA¹, A², O³, cis-AB, O¹-A² hybrid	8,32-35	19
NheI	+	526	C → G	B, O¹-B hybrids	6,32	14,36
MboI	−	646	T → A	A^x, A^x hybrids, O^1v	9,15,31	14
HpaII	−	703	G → A	B, O¹-B hybrids	6,32	19
DdeI	−	771	C → T	A^x hybrids,O^1v	31	15,31
—	+	796	C → A	B	6	36
—	+	802	G → A	O²	10	36
—	+	803	G → C	B	6	36
—	+	798-804	+G	A^el, O³	11,35	11
SalI	−	871	G → A	A³, B^x	7,13	14
—	+	1059-1061	−C	A², O³	34,35	14
HpaII	−	1096	G → A	B, O²	19	19

This list of alleles is not complete.