Table 1. Frequencies of aberrant... | American Society of Hematology

Table 1.

Frequencies of aberrant phenotypes

Aberrant phenotypes	Number of cases
Cross-lineage infidelity, 37 of 126 (29%)
CD2	26 (21)
CD7	11 (9)
CD19	3 (2)
CD20	1 (0.8)
CD5	1 (0.8)
Antigen overexpression, 26 of 126 (21%)
CD33⁺⁺⁺	14 (11)
CD34	11 (9)
CD13	3 (2)
CD117	1 (0.8)
CD15^*	1 (0.8)
HLA DR	1 (0.8)
Abnormal light scatter, 22 of 126 (17%)
High FSC/SSC
CD2	4 (2.6)
CD34	4 (2.6)
CD7	4 (2.6)
CD117	2 (1.5)
CD19	2 (1.5)
CD20	1 (0.8)
Low FSC/SSC
CD13^†	3 (2)
CD33^†	1 (0.8)
CD15	1 (0.8)
Asynchronous antigen expression, 98 of 126 (78%)
CD34⁺ HLA-DR⁻CD33⁺	11 (9)
CD34⁺CD56⁺	10 (8)
CD34⁺CD11b⁺	6 (5)
CD34⁺CD33⁺⁺	4 (3)
CD34⁺CD14⁺	4 (3)
CD34⁺ CD117⁺HLA-DR⁻	3 (2.3)
CD34⁺CD117⁻ CD15⁺	3 (2.3)
CD34⁺ CD33⁻ CD13⁺HLA-DR⁺	2 (1.5)
CD34⁺CD33⁻ CD13⁺ HLA-DR⁻	1 (0.8)
CD34⁺ CD33⁻ CD117⁺HLA-DR⁺	1 (0.8)
CD117⁺CD33⁺ HLA-DR⁻	14 (11)
CD117⁺ CD34⁻CD15⁻^‡	8 (6)
CD117⁺CD11b⁺	7 (5.5)
CD117⁺CD33⁺ CD34⁻ CD15⁺	5 (4)
CD117⁺ DR⁻ CD15⁺	3 (2.3)
CD117⁺ DR⁻CD15⁻^*	2 (2.3)
CD117⁺DR⁺ CD33⁺ CD34⁻	1 (0.8)
CD33⁺⁺ HLA-DR⁻ CD34⁻CD15⁻ CD14⁻	22 (17)
CD33⁻ CD13⁺	18 (14)
CD33⁺ CD13⁻	9 (7)
CD33⁺ HLA-DR⁺ CD4⁺CD45^dim	1 (0.8)
CD33⁺⁺HLA-DR⁺ CD15⁻CD14⁻^1-153	1 (0.8)
CD33⁺CD45d CD34⁻ CD15⁻^1-155	1 (0.8)
CD33⁺ HLA-DR⁺ CD56⁺CD13⁺	1 (0.8)

Aberrant phenotypes	Number of cases
Cross-lineage infidelity, 37 of 126 (29%)
CD2	26 (21)
CD7	11 (9)
CD19	3 (2)
CD20	1 (0.8)
CD5	1 (0.8)
Antigen overexpression, 26 of 126 (21%)
CD33⁺⁺⁺	14 (11)
CD34	11 (9)
CD13	3 (2)
CD117	1 (0.8)
CD15^*	1 (0.8)
HLA DR	1 (0.8)
Abnormal light scatter, 22 of 126 (17%)
High FSC/SSC
CD2	4 (2.6)
CD34	4 (2.6)
CD7	4 (2.6)
CD117	2 (1.5)
CD19	2 (1.5)
CD20	1 (0.8)
Low FSC/SSC
CD13^†	3 (2)
CD33^†	1 (0.8)
CD15	1 (0.8)
Asynchronous antigen expression, 98 of 126 (78%)
CD34⁺ HLA-DR⁻CD33⁺	11 (9)
CD34⁺CD56⁺	10 (8)
CD34⁺CD11b⁺	6 (5)
CD34⁺CD33⁺⁺	4 (3)
CD34⁺CD14⁺	4 (3)
CD34⁺ CD117⁺HLA-DR⁻	3 (2.3)
CD34⁺CD117⁻ CD15⁺	3 (2.3)
CD34⁺ CD33⁻ CD13⁺HLA-DR⁺	2 (1.5)
CD34⁺CD33⁻ CD13⁺ HLA-DR⁻	1 (0.8)
CD34⁺ CD33⁻ CD117⁺HLA-DR⁺	1 (0.8)
CD117⁺CD33⁺ HLA-DR⁻	14 (11)
CD117⁺ CD34⁻CD15⁻^‡	8 (6)
CD117⁺CD11b⁺	7 (5.5)
CD117⁺CD33⁺ CD34⁻ CD15⁺	5 (4)
CD117⁺ DR⁻ CD15⁺	3 (2.3)
CD117⁺ DR⁻CD15⁻^*	2 (2.3)
CD117⁺DR⁺ CD33⁺ CD34⁻	1 (0.8)
CD33⁺⁺ HLA-DR⁻ CD34⁻CD15⁻ CD14⁻	22 (17)
CD33⁻ CD13⁺	18 (14)
CD33⁺ CD13⁻	9 (7)
CD33⁺ HLA-DR⁺ CD4⁺CD45^dim	1 (0.8)
CD33⁺⁺HLA-DR⁺ CD15⁻CD14⁻^1-153	1 (0.8)
CD33⁺CD45d CD34⁻ CD15⁻^1-155	1 (0.8)
CD33⁺ HLA-DR⁺ CD56⁺CD13⁺	1 (0.8)

Overexpression of CD15 in nongranulocytic lineage.

Basophilic lineage.

Mast cells express this phenotype with a higher expression of CD117.

Dendritic cells.

Basophilic lineage.