Multivariate analysis of clinical and biological parameters
| . | Total population (N = 108) . | Young patients (≤ 57 years) (N = 52) . | ||
|---|---|---|---|---|
| DFS (P) . | OS (P) . | DFS (P) . | OS (P) . | |
| 5NT mRNA levels | .02* | .16 | .003* | .01* |
| Age | .06 | .03* | — | — |
| Karyotype | .0004* | .42 | .03* | .12 |
| Platelet counts | .004* | NE | NE | NE |
| ABMT | .28 | .64 | NE | NE |
| Presence of relapse | NE | .03 | NE | .21 |
| Response to IT | NE | < .00001* | NE | < .001* |
| . | Total population (N = 108) . | Young patients (≤ 57 years) (N = 52) . | ||
|---|---|---|---|---|
| DFS (P) . | OS (P) . | DFS (P) . | OS (P) . | |
| 5NT mRNA levels | .02* | .16 | .003* | .01* |
| Age | .06 | .03* | — | — |
| Karyotype | .0004* | .42 | .03* | .12 |
| Platelet counts | .004* | NE | NE | NE |
| ABMT | .28 | .64 | NE | NE |
| Presence of relapse | NE | .03 | NE | .21 |
| Response to IT | NE | < .00001* | NE | < .001* |
DFS, disease-free survival; OS, overall survival; 5NT: high Km 5-nucleotidase; mRNA, messenger RNA; NE, not evaluated; ABMT: autologous-bone marrow transplantation; IT: induction therapy.
Statistically significant.