Presentation features of patients in Medical Research Council AML11
Parameter . | Value . | No. of patients . | Percentage of patients* . | ||
---|---|---|---|---|---|
DAT . | ADE . | MAC . | |||
Age | < 56 | 6 | 5 | 9 | 2 |
56-59 | 37 | 37 | 75 | 11 | |
60-64 | 92 | 95 | 186 | 28 | |
65-69 | 105 | 101 | 207 | 32 | |
70-74 | 69 | 65 | 137 | 21 | |
75-79 | 18 | 17 | 39 | 6 | |
80 | 1 | 3 | 3 | 1 | |
Sex | Male | 185 | 184 | 368 | 56 |
Female | 143 | 143 | 288 | 44 | |
Type of AML | De novo | 247 | 250 | 502 | 76 |
Secondary | 78 | 74 | 147 | 23 | |
Not AML | 3 | 3 | 7 | 1 | |
White blood count, × 109/L | 0-9 | 157 | 169 | 315 | 49 |
10-99 | 136 | 118 | 241 | 38 | |
100-199 | 18 | 24 | 61 | 8 | |
200 | 10 | 10 | 22 | 3 | |
Unknown | 7 | 6 | 17 | 3 | |
FAB type | M0 | 13 | 13 | 25 | 4 |
M1 | 76 | 81 | 166 | 25 | |
M2 | 83 | 86 | 174 | 26 | |
M3 | 15 | 14 | 30 | 5 | |
M4 | 56 | 55 | 93 | 15 | |
M5 | 32 | 24 | 56 | 9 | |
M6 | 8 | 12 | 26 | 4 | |
M7 | 5 | 3 | 10 | 1 | |
RAEB-T | 3 | 2 | 5 | 1 | |
Unknown | 37 | 37 | 71 | 11 | |
Performance status | 0 | 154 | 154 | 308 | 47 |
1 | 120 | 120 | 241 | 37 | |
2 | 27 | 27 | 53 | 8 | |
3 | 23 | 21 | 43 | 7 | |
4 | 4 | 5 | 11 | 2 | |
Cytogenetic group | Favorable | 19 | 18 | 40 | 6 |
Intermediate | 215 | 216 | 419 | 65 | |
Adverse | 39 | 35 | 71 | 11 | |
Unknown | 55 | 58 | 126 | 18 |
Parameter . | Value . | No. of patients . | Percentage of patients* . | ||
---|---|---|---|---|---|
DAT . | ADE . | MAC . | |||
Age | < 56 | 6 | 5 | 9 | 2 |
56-59 | 37 | 37 | 75 | 11 | |
60-64 | 92 | 95 | 186 | 28 | |
65-69 | 105 | 101 | 207 | 32 | |
70-74 | 69 | 65 | 137 | 21 | |
75-79 | 18 | 17 | 39 | 6 | |
80 | 1 | 3 | 3 | 1 | |
Sex | Male | 185 | 184 | 368 | 56 |
Female | 143 | 143 | 288 | 44 | |
Type of AML | De novo | 247 | 250 | 502 | 76 |
Secondary | 78 | 74 | 147 | 23 | |
Not AML | 3 | 3 | 7 | 1 | |
White blood count, × 109/L | 0-9 | 157 | 169 | 315 | 49 |
10-99 | 136 | 118 | 241 | 38 | |
100-199 | 18 | 24 | 61 | 8 | |
200 | 10 | 10 | 22 | 3 | |
Unknown | 7 | 6 | 17 | 3 | |
FAB type | M0 | 13 | 13 | 25 | 4 |
M1 | 76 | 81 | 166 | 25 | |
M2 | 83 | 86 | 174 | 26 | |
M3 | 15 | 14 | 30 | 5 | |
M4 | 56 | 55 | 93 | 15 | |
M5 | 32 | 24 | 56 | 9 | |
M6 | 8 | 12 | 26 | 4 | |
M7 | 5 | 3 | 10 | 1 | |
RAEB-T | 3 | 2 | 5 | 1 | |
Unknown | 37 | 37 | 71 | 11 | |
Performance status | 0 | 154 | 154 | 308 | 47 |
1 | 120 | 120 | 241 | 37 | |
2 | 27 | 27 | 53 | 8 | |
3 | 23 | 21 | 43 | 7 | |
4 | 4 | 5 | 11 | 2 | |
Cytogenetic group | Favorable | 19 | 18 | 40 | 6 |
Intermediate | 215 | 216 | 419 | 65 | |
Adverse | 39 | 35 | 71 | 11 | |
Unknown | 55 | 58 | 126 | 18 |
DAT indicates daunorubicin, cytarabine, and thioguanine; ADE, daunorubicin, cytarabine, and etoposide; MAC, mitoxantrone-cytarabine; AML, acute myeloid leukemia; FAB, French-American-British; RAEB-T, refractory anemia with excess blasts in transformation; ALL, acute lymphoblastic leukemia.
Percentages may not add up to 100 because of rounding.