Table 3.

Donor cell engraftment

GroupnH-2Dd (%)
Vehicle 94.7 ± 1.4 
WHI-P131 94.5 ± 2.3  
MTX 97.6 ± 1.0 
WHI-P131 + MTX 97.0 ± 2.0  
Syngeneic controls 0.0 ± 0.0 
GroupnH-2Dd (%)
Vehicle 94.7 ± 1.4 
WHI-P131 94.5 ± 2.3  
MTX 97.6 ± 1.0 
WHI-P131 + MTX 97.0 ± 2.0  
Syngeneic controls 0.0 ± 0.0 

Vehicle-treated mice were analyzed at the time of death between 50 and 77 days. All other mice were electively killed and analyzed at the end of the 85-day observation period. Data are presented as mean ± SEM values for the percentage of H-2Dd-positive donor cells in the nucleated peripheral blood cell population.

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