Table 2.

Concentration of Ro 31-9790 in the plasma of mice

Treatment of animals*Time after injection of CFSE-labeled cells
30 min60 min120 min
3 mg 63 ± 17 81.6 ± 27 16.5 
2 mg nd 18 nd 
1 mg nd 17 nd 
Treatment of animals*Time after injection of CFSE-labeled cells
30 min60 min120 min
3 mg 63 ± 17 81.6 ± 27 16.5 
2 mg nd 18 nd 
1 mg nd 17 nd 

CFSE indicates carboxyfluorescein diacetate succidinimidyl ester; nd, not determined.

*

1, 2, and 3 mg/mouse equivalent to 33, 66, and 100 mg/kg body weight, respectively. Results are mean plasma levels of Ro 31-9790 (μM) ± SD (n = 5).

n = 2.

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