Detection of cytokine expression in Tax+peripheral blood mononuclear cells isolated from asymptomatic carriers of human T-cell lymphotropic virus type I and patients with HTLV-I–associated neurological disease
Patient . | Cytokine-expressing cells (%) in Tax+ PBMCs* . | |||
---|---|---|---|---|
TNF-α . | IFN-γ . | IL-2 . | IL-4 . | |
TAF | 0.0 | 10.7 | 0.1 | 0.0 |
TAT | 0.3 | 5.4 | 0.3 | 0.0 |
TXX | 4.7 | 21.4 | 0.0 | 0.0 |
HH | 0.0 | 3.8 | 0.0 | 0.0 |
HS | 0.0 | 2.8 | 1.5 | 0.0 |
HT | 2.4 | 11.6 | 0.0 | 0.0 |
Patient . | Cytokine-expressing cells (%) in Tax+ PBMCs* . | |||
---|---|---|---|---|
TNF-α . | IFN-γ . | IL-2 . | IL-4 . | |
TAF | 0.0 | 10.7 | 0.1 | 0.0 |
TAT | 0.3 | 5.4 | 0.3 | 0.0 |
TXX | 4.7 | 21.4 | 0.0 | 0.0 |
HH | 0.0 | 3.8 | 0.0 | 0.0 |
HS | 0.0 | 2.8 | 1.5 | 0.0 |
HT | 2.4 | 11.6 | 0.0 | 0.0 |
The cells were cultivated for 12 hours with 1 μM monensin.