Clinical symptoms in affected members of the families investigated
| Family . | Patient . | Generation . | Sex . | Degree of bruising . | Prolonged bleeding from cuts . | Epistaxes . | Bleeding after dental extraction . | Gastrointestinal tract bleeding . | Menorrhagia . |
|---|---|---|---|---|---|---|---|---|---|
| F1 | P1 | II:1 | M | + | Unknown | None | ++ | ++ | N/A |
| F1 | P2 | III:1 | F | ++ | + | None | + | None | ++ |
| F1 | P3 | IV:1 | F | ++ | + | + | + | None | ++ |
| F1 | P4 | V:1 | F | No clinical symptoms to date (baby) | |||||
| F2 | P1 | I:1 | F | No clinical symptoms to date | |||||
| F2 | P2 | II:1 | F | + | Unknown | + | Unknown | ++ | ++ |
| F3 | P1 | — | F | — | Unknown | Unknown | Unknown | None | +++ |
| Family . | Patient . | Generation . | Sex . | Degree of bruising . | Prolonged bleeding from cuts . | Epistaxes . | Bleeding after dental extraction . | Gastrointestinal tract bleeding . | Menorrhagia . |
|---|---|---|---|---|---|---|---|---|---|
| F1 | P1 | II:1 | M | + | Unknown | None | ++ | ++ | N/A |
| F1 | P2 | III:1 | F | ++ | + | None | + | None | ++ |
| F1 | P3 | IV:1 | F | ++ | + | + | + | None | ++ |
| F1 | P4 | V:1 | F | No clinical symptoms to date (baby) | |||||
| F2 | P1 | I:1 | F | No clinical symptoms to date | |||||
| F2 | P2 | II:1 | F | + | Unknown | + | Unknown | ++ | ++ |
| F3 | P1 | — | F | — | Unknown | Unknown | Unknown | None | +++ |