Difficult cases of myelodysplastic syndrome
| Number . | Sex . | Race . | Age . | Initial BM diagnosis MDS . | Review BM diagnosis MDS . | Morphology indeterminate . | Cytogenetics clonal abnormality . | Final diagnosis . | Erythroid . | Megakaryocytic . | Myeloid . | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Morphology dysplasia . | Flow dysplasia . | Morphology dysplasia . | Flow dysplasia . | Morphology dysplasia . | Flow dysplasia . | |||||||||
| 1 | M | W | 80 | − | +* | + | RA | + | + | + | − | + | + | |
| 2 | M | W | 45 | − | +* | − | RA | + | − | − | − | − | + | |
| 3 | F | W | 28 | − | +* | − | RA | + | − | − | + | − | + | |
| 4 | F | W | 69 | + | +* | + | RA | + | + | + | + | + | − (NE) | |
| 5 | M | W | 70 | − | +* | + | RA | + | + | + | − | + | + | |
| 6 | F | W | 61 | − | +* | + | RA | − | + | + | + | − | + | |
| 7 | M | W | 27 | − | +* | − | RA | − (NE) | − | − (NE) | − | − (NE) | + | |
| 8 | F | B | 41 | − | +* | − | RA | − (NE) | − | − (NE) | + | − (NE) | − | |
| 9 | M | W | 64 | − | +* | NE | RA | + | + | + | − | + | + | |
| 10 | M | A | 72 | − | +* | + | RAEB | + | + | − | − | + | + | |
| 11 | M | W | 72 | − | +* | − | RAEB | + | + | + | + | + | + | |
| 12 | M | W | 68 | + | +* | − | RAEB | + | + | − (NE) | − | + | + | |
| 13 | M | W | 55 | − | − | x | − | RA | + | − | − | − | − | − |
| 14 | M | W | 54 | − | − | x | − | RA | − | − | + | + | − | + |
| 15 | M | W | 59 | − | − | x | − | RA | − (NE) | + | − (NE) | − | − (NE) | + |
| 16 | F | B | 55 | − | − | x | − | RA | + | + | − | − | − | + |
| 17 | F | W | 57 | − | − | x | NE | RA | − | + | − | − | − | + |
| 18 | F | H | 37 | − | − | x | − | RA | + | + | + | + | + | + |
| 19 | M | W | 70 | − | − | x | − | RA | − | − | + | + | + | + |
| 20 | F | W | 42 | + | − | x | − | RA | − | − | − | − | − | + |
| Number . | Sex . | Race . | Age . | Initial BM diagnosis MDS . | Review BM diagnosis MDS . | Morphology indeterminate . | Cytogenetics clonal abnormality . | Final diagnosis . | Erythroid . | Megakaryocytic . | Myeloid . | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Morphology dysplasia . | Flow dysplasia . | Morphology dysplasia . | Flow dysplasia . | Morphology dysplasia . | Flow dysplasia . | |||||||||
| 1 | M | W | 80 | − | +* | + | RA | + | + | + | − | + | + | |
| 2 | M | W | 45 | − | +* | − | RA | + | − | − | − | − | + | |
| 3 | F | W | 28 | − | +* | − | RA | + | − | − | + | − | + | |
| 4 | F | W | 69 | + | +* | + | RA | + | + | + | + | + | − (NE) | |
| 5 | M | W | 70 | − | +* | + | RA | + | + | + | − | + | + | |
| 6 | F | W | 61 | − | +* | + | RA | − | + | + | + | − | + | |
| 7 | M | W | 27 | − | +* | − | RA | − (NE) | − | − (NE) | − | − (NE) | + | |
| 8 | F | B | 41 | − | +* | − | RA | − (NE) | − | − (NE) | + | − (NE) | − | |
| 9 | M | W | 64 | − | +* | NE | RA | + | + | + | − | + | + | |
| 10 | M | A | 72 | − | +* | + | RAEB | + | + | − | − | + | + | |
| 11 | M | W | 72 | − | +* | − | RAEB | + | + | + | + | + | + | |
| 12 | M | W | 68 | + | +* | − | RAEB | + | + | − (NE) | − | + | + | |
| 13 | M | W | 55 | − | − | x | − | RA | + | − | − | − | − | − |
| 14 | M | W | 54 | − | − | x | − | RA | − | − | + | + | − | + |
| 15 | M | W | 59 | − | − | x | − | RA | − (NE) | + | − (NE) | − | − (NE) | + |
| 16 | F | B | 55 | − | − | x | − | RA | + | + | − | − | − | + |
| 17 | F | W | 57 | − | − | x | NE | RA | − | + | − | − | − | + |
| 18 | F | H | 37 | − | − | x | − | RA | + | + | + | + | + | + |
| 19 | M | W | 70 | − | − | x | − | RA | − | − | + | + | + | + |
| 20 | F | W | 42 | + | − | x | − | RA | − | − | − | − | − | + |
For abbreviations, see Table 1.
Diagnosis could not be made based upon a single specimen.