Characteristics of 55 patients with parainfluenza virus-3 lower respiratory tract infections, according to ribavirin therapy
| Characteristic . | Treated with ribavirin (n = 31) . | No ribavirin (n = 24) . |
|---|---|---|
| Underlying disease | ||
| Acute leukemia | 11 (35%) | 10 (42%) |
| CML | 8 (26%) | 8 (33%) |
| HD/MM/NHL | 6 (19%) | 4 (17%) |
| MDS | 3 (10%) | 0 (0%) |
| Other | 3 (10%) | 2 (8%) |
| Donor type | ||
| Matched related | 10 (32%) | 8 (33%) |
| Mismatched/unrelated | 16 (52%) | 11 (46%) |
| Autologous | 5 (16%) | 5 (21%) |
| Acute GVHD5-150 | ||
| Grade 0-II | 16 (62%) | 10 (56%) |
| Grade III-IV | 10 (38%) | 8 (44%) |
| Engrafted at diagnosis? | ||
| Yes | 21 (68%) | 19 (79%) |
| No | 10 (32%) | 5 (21%) |
| Ventilated at diagnosis? | ||
| Yes | 4 (13%) | 1 (4%) |
| No | 27 (87%) | 23 (96%) |
| Oxygen requirement at diagnosis? | ||
| Yes | 15 (48%) | 9 (38%) |
| No | 16 (52%) | 15 (62%) |
| Characteristic . | Treated with ribavirin (n = 31) . | No ribavirin (n = 24) . |
|---|---|---|
| Underlying disease | ||
| Acute leukemia | 11 (35%) | 10 (42%) |
| CML | 8 (26%) | 8 (33%) |
| HD/MM/NHL | 6 (19%) | 4 (17%) |
| MDS | 3 (10%) | 0 (0%) |
| Other | 3 (10%) | 2 (8%) |
| Donor type | ||
| Matched related | 10 (32%) | 8 (33%) |
| Mismatched/unrelated | 16 (52%) | 11 (46%) |
| Autologous | 5 (16%) | 5 (21%) |
| Acute GVHD5-150 | ||
| Grade 0-II | 16 (62%) | 10 (56%) |
| Grade III-IV | 10 (38%) | 8 (44%) |
| Engrafted at diagnosis? | ||
| Yes | 21 (68%) | 19 (79%) |
| No | 10 (32%) | 5 (21%) |
| Ventilated at diagnosis? | ||
| Yes | 4 (13%) | 1 (4%) |
| No | 27 (87%) | 23 (96%) |
| Oxygen requirement at diagnosis? | ||
| Yes | 15 (48%) | 9 (38%) |
| No | 16 (52%) | 15 (62%) |
CML indicates chronic myelogenous leukemia; HD, Hodgkin disease; MM, multiple myeloma; NHL, non-Hodgkin lymphoma; MDS, myelodysplasia; GVHD, graft-versus-host disease.
Allogeneic recipients only.