Median decrease in platelet count (×10−3/μL) 3 minutes after indicated agents were injected
| . | Tissue factor . | Collagen + epinephrine . | ADP . | Saline . |
|---|---|---|---|---|
| WT (β3+/+) | 429 | 424 | 289 | 62 |
| n = 11 | n = 11 | n = 6 | n = 3 | |
| NULL (β3−/−) | 334 | 2684-150 | 904-150 | 92 |
| n = 8 | n = 11 | n = 5 | n = 5 | |
| WT + 1B5 Fab | ND | ND | 1144-150 | ND |
| n = 8 |
| . | Tissue factor . | Collagen + epinephrine . | ADP . | Saline . |
|---|---|---|---|---|
| WT (β3+/+) | 429 | 424 | 289 | 62 |
| n = 11 | n = 11 | n = 6 | n = 3 | |
| NULL (β3−/−) | 334 | 2684-150 | 904-150 | 92 |
| n = 8 | n = 11 | n = 5 | n = 5 | |
| WT + 1B5 Fab | ND | ND | 1144-150 | ND |
| n = 8 |
WT indicates wild type; ND, not determined.
P < .01 (vs WT β3+/+).