Transduced peripheral blood cells 4 to 7 weeks after transplantation
| Experiment . | Vector MOI . | Number of mice . | Reporter gene . | Weeks after transplant . | Average %(+) RBCs ±SD . | Average %(+) WBCs ±SD . | Average %(+) PLTs ±SD . |
|---|---|---|---|---|---|---|---|
| 1 | 0.6 | 4 | GFP | 4 | 38 ± 10 | 23 ± 8 | 14 ± 11 |
| 2 | 1.0 | 3 | AP | 6 | 11 ± 1 | 30 ± 22 | ND |
| 3 | 1.6 | 3 | AP | 6 | 9 ± 3 | 17 ± 20 | ND |
| 4 | 1.8 | 3 | AP | 4 | 61 ± 28 | 20 ± 18 | ND |
| 5 | 2.2 | 3 | GFP | 4 | 25 ± 7 | 4.5 ± 1.5 | 35 ± 22 |
| 6 | 2.6 | 4 | AP | 4 | 58 ± 22 | 55 ± 6 | ND |
| 7 | 5.0 | 1 | GFP | 4 | 62 | 5 | 28 |
| 8 | 5.2 | 1 | AP | 7 | 26 | 38 | ND |
| Experiment . | Vector MOI . | Number of mice . | Reporter gene . | Weeks after transplant . | Average %(+) RBCs ±SD . | Average %(+) WBCs ±SD . | Average %(+) PLTs ±SD . |
|---|---|---|---|---|---|---|---|
| 1 | 0.6 | 4 | GFP | 4 | 38 ± 10 | 23 ± 8 | 14 ± 11 |
| 2 | 1.0 | 3 | AP | 6 | 11 ± 1 | 30 ± 22 | ND |
| 3 | 1.6 | 3 | AP | 6 | 9 ± 3 | 17 ± 20 | ND |
| 4 | 1.8 | 3 | AP | 4 | 61 ± 28 | 20 ± 18 | ND |
| 5 | 2.2 | 3 | GFP | 4 | 25 ± 7 | 4.5 ± 1.5 | 35 ± 22 |
| 6 | 2.6 | 4 | AP | 4 | 58 ± 22 | 55 ± 6 | ND |
| 7 | 5.0 | 1 | GFP | 4 | 62 | 5 | 28 |
| 8 | 5.2 | 1 | AP | 7 | 26 | 38 | ND |
WBC values include lymphocytes, monocytes, and granulocytes. PLTs were not scored for AP because of difficulties identifying AP− PLTs.
MOI indicates multiplicity of infection; RBCs, red blood cells; WBCs, white blood cells; PLTs, platelets; GFP, green fluorescent protein; AP, alkaline phosphate; ND, not done.