Phagocyte accumulation on the surfaces of variously treated polyethylene terephthalate disks after implantation for 16 hours in Swiss Webster mice
Sample coating . | Peroxidase activity (mU/cm2) . | PMNs* (× 104/cm2) . | NSE activity (mU/cm2) . | Mφs* (× 104/cm2) . |
---|---|---|---|---|
Fibrinogen | 2.42 ± 1.32 | 10.52 ± 5.74 | 2.10 ± 0.17 | 19.09 ± 1.54 |
D100 | 2.27 ± 0.58 | 9.87 ± 2.52 | 2.19 ± 0.72 | 19.91 ± 6.55 |
D30 | 2.44 ± 1.45 | 10.61 ± 6.30 | 3.52 ± 0.87 | 32.00 ± 7.91 |
E | 0.042 ± 0.074† | 0.18 ± 0.32† | 0.094 ± 0.041† | 0.85 ± 0.37† |
Albumin | 0.026 ± 0.040† | 0.11 ± 0.17† | 0.14 ± 0.10† | 1.27 ± 0.91† |
Sample coating . | Peroxidase activity (mU/cm2) . | PMNs* (× 104/cm2) . | NSE activity (mU/cm2) . | Mφs* (× 104/cm2) . |
---|---|---|---|---|
Fibrinogen | 2.42 ± 1.32 | 10.52 ± 5.74 | 2.10 ± 0.17 | 19.09 ± 1.54 |
D100 | 2.27 ± 0.58 | 9.87 ± 2.52 | 2.19 ± 0.72 | 19.91 ± 6.55 |
D30 | 2.44 ± 1.45 | 10.61 ± 6.30 | 3.52 ± 0.87 | 32.00 ± 7.91 |
E | 0.042 ± 0.074† | 0.18 ± 0.32† | 0.094 ± 0.041† | 0.85 ± 0.37† |
Albumin | 0.026 ± 0.040† | 0.11 ± 0.17† | 0.14 ± 0.10† | 1.27 ± 0.91† |
D100, D30, and E are purified plasmin degradation fragments of fibrinogen.
PMN indicates polymorphonuclear neutrophils; NSE, nonspecific esterase; Mφs, macrophages/monocytes.
Phagocyte numbers calculated on the basis of measured activities of MPO for PMN and NSE for Mφs.
Differs from fibrinogen coating at P < .01.