Table 1.

Phagocyte accumulation on the surfaces of variously treated polyethylene terephthalate disks after implantation for 16 hours in Swiss Webster mice

Sample
coating
Peroxidase activity
(mU/cm2)
PMNs*
(× 104/cm2)
NSE activity
(mU/cm2)
Mφs*
(× 104/cm2)
Fibrinogen 2.42 ± 1.32 10.52 ± 5.74 2.10 ± 0.17 19.09 ± 1.54 
D100 2.27 ± 0.58 9.87 ± 2.52 2.19 ± 0.72 19.91 ± 6.55 
D30 2.44 ± 1.45 10.61 ± 6.30 3.52 ± 0.87 32.00 ± 7.91 
0.042 ± 0.074 0.18 ± 0.32 0.094 ± 0.041 0.85 ± 0.37 
Albumin 0.026 ± 0.040 0.11 ± 0.17 0.14 ± 0.10 1.27 ± 0.91 
Sample
coating
Peroxidase activity
(mU/cm2)
PMNs*
(× 104/cm2)
NSE activity
(mU/cm2)
Mφs*
(× 104/cm2)
Fibrinogen 2.42 ± 1.32 10.52 ± 5.74 2.10 ± 0.17 19.09 ± 1.54 
D100 2.27 ± 0.58 9.87 ± 2.52 2.19 ± 0.72 19.91 ± 6.55 
D30 2.44 ± 1.45 10.61 ± 6.30 3.52 ± 0.87 32.00 ± 7.91 
0.042 ± 0.074 0.18 ± 0.32 0.094 ± 0.041 0.85 ± 0.37 
Albumin 0.026 ± 0.040 0.11 ± 0.17 0.14 ± 0.10 1.27 ± 0.91 

D100, D30, and E are purified plasmin degradation fragments of fibrinogen.

PMN indicates polymorphonuclear neutrophils; NSE, nonspecific esterase; Mφs, macrophages/monocytes.

*

Phagocyte numbers calculated on the basis of measured activities of MPO for PMN and NSE for Mφs.

Differs from fibrinogen coating at P < .01.

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