Comparison of steady-state biological data in the patients homozygous for hemoglobin S with and without CD36 deficiency (mean ± SD)
| . | CD36− SS patients (n = 14) . | Matched CD36+ SS patients (n = 31) . | P . |
|---|---|---|---|
| Hb (11.5-17.7 g/dL) | 8.31 ± 1.19 | 8.99 ± 1.13 | .08 |
| Hb F (<1%) | 3.2 ± 2.5 | 5.1 ± 5.1 | .30 |
| Reticulocytes (25-100 × 109/L) | 318 ± 95 | 259 ± 91 | .09 |
| Leukocytes (4-10 × 109/L) | 11.6 ± 3.6 | 10.3 ± 3.5 | .26 |
| Total bilirubin (4-21 μM) | 55.8 ± 35.3 | 59.8 ± 28.1 | .38 |
| LDH (100-250 IU/L) | 429 ± 263 | 476 ± 305 | .88 |
| Uric acid (145-460 μM) | 347 ± 69 | 330 ± 87 | .52 |
| Creatinine (60-130 μM) | 46 ± 15 | 50 ± 15 | .47 |
| AST (5-40 IU/l) | 39 ± 14 | 42 ± 15 | .53 |
| ALT (5-45 IU/l) | 28 ± 12 | 29 ± 23 | .34 |
| . | CD36− SS patients (n = 14) . | Matched CD36+ SS patients (n = 31) . | P . |
|---|---|---|---|
| Hb (11.5-17.7 g/dL) | 8.31 ± 1.19 | 8.99 ± 1.13 | .08 |
| Hb F (<1%) | 3.2 ± 2.5 | 5.1 ± 5.1 | .30 |
| Reticulocytes (25-100 × 109/L) | 318 ± 95 | 259 ± 91 | .09 |
| Leukocytes (4-10 × 109/L) | 11.6 ± 3.6 | 10.3 ± 3.5 | .26 |
| Total bilirubin (4-21 μM) | 55.8 ± 35.3 | 59.8 ± 28.1 | .38 |
| LDH (100-250 IU/L) | 429 ± 263 | 476 ± 305 | .88 |
| Uric acid (145-460 μM) | 347 ± 69 | 330 ± 87 | .52 |
| Creatinine (60-130 μM) | 46 ± 15 | 50 ± 15 | .47 |
| AST (5-40 IU/l) | 39 ± 14 | 42 ± 15 | .53 |
| ALT (5-45 IU/l) | 28 ± 12 | 29 ± 23 | .34 |
Normal values are given in parentheses.
SS indicates homozygous for hemoglobin S; Hb, hemoglobin; LDH, lactate dehydrogenase; AST, aspartate aminotransferase; ALT, alanine aminotransferase.