Peripheral blood leukocyte counts in mice challenged withBurkholderia cepacia
| Group4-150 . | N . | White blood cells . | Neutrophils (%) . | Neutrophil count . | NBT-positive neutrophils . |
|---|---|---|---|---|---|
| X-CGD | 6 | 18 500 ± 5 300 | 10 ± 6 | 1 920 ± 1 576 | 0 |
| WT/X-CGD chimera | |||||
| 9%-16% | 9 | 17 200 ± 5 700 | 8 ± 5 | 1 298 ± 582 | 68 ± 86 |
| 20%-26% | 5 | 19 100 ± 5 600 | 8 ± 4 | 1 562 ± 1 030 | 359 ± 238 |
| 32%-41% | 9 | 25 400 ± 10 500 | 11 ± 6 | 2 686 ± 2 068 | 1 024 ± 866 |
| MSCVm91Neo/X-CGD chimera | |||||
| 30%-42% | 7 | 15 200 ± 4 500 | 13 ± 5 | 1 988 ± 1 057 | 740 ± 461 |
| Group4-150 . | N . | White blood cells . | Neutrophils (%) . | Neutrophil count . | NBT-positive neutrophils . |
|---|---|---|---|---|---|
| X-CGD | 6 | 18 500 ± 5 300 | 10 ± 6 | 1 920 ± 1 576 | 0 |
| WT/X-CGD chimera | |||||
| 9%-16% | 9 | 17 200 ± 5 700 | 8 ± 5 | 1 298 ± 582 | 68 ± 86 |
| 20%-26% | 5 | 19 100 ± 5 600 | 8 ± 4 | 1 562 ± 1 030 | 359 ± 238 |
| 32%-41% | 9 | 25 400 ± 10 500 | 11 ± 6 | 2 686 ± 2 068 | 1 024 ± 866 |
| MSCVm91Neo/X-CGD chimera | |||||
| 30%-42% | 7 | 15 200 ± 4 500 | 13 ± 5 | 1 988 ± 1 057 | 740 ± 461 |
The percentage of nitroblue tetrazolium (NBT)-positive peripheral blood neutrophils is as indicated for the transplantation chimera groups. Total white blood cells, neutrophils, and NBT-positive neutrophils are indicated per cubic millimeter and were obtained prior to challenge with B cepacia.
X-CGD indicates X-linked chronic granulomatous disease; WT, wild-type.