Table 6.

Engraftment of sorted subpopulations in nonobese diabetic-severe combined immunodeficient mice

PatientSubpopulationNo. cells injected per mouseCD45+
wks 8-12 (%)
FISH
No. cells abnormal/
no. analyzed
Abnormal (%)
SP+CD34+CD38 2 × 105   
  1 × 105 0.77, 0.21 0/258, 0/67 
 SPCD34+CD38 1 × 105   
  3 × 105   
  1 × 106 0.6 26/44 55 
 SP+CD34CD38 3.7 × 104   
SP+CD34+CD38 8.7 × 104 0.34 0/55 
 SPCD34+CD38 8.7 × 104   
  1.8 × 105   
 SP+CD34CD38 8.7 × 104   
PatientSubpopulationNo. cells injected per mouseCD45+
wks 8-12 (%)
FISH
No. cells abnormal/
no. analyzed
Abnormal (%)
SP+CD34+CD38 2 × 105   
  1 × 105 0.77, 0.21 0/258, 0/67 
 SPCD34+CD38 1 × 105   
  3 × 105   
  1 × 106 0.6 26/44 55 
 SP+CD34CD38 3.7 × 104   
SP+CD34+CD38 8.7 × 104 0.34 0/55 
 SPCD34+CD38 8.7 × 104   
  1.8 × 105   
 SP+CD34CD38 8.7 × 104   

See Tables 2 and 5 for abbreviations.

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