Fluorescence in situ hybridization of sorted cells
| Patient . | Cytogenetic marker at diagnosis (% abnormal)3-150 . | SP+CD34+CD38− . | SP−CD34+CD38− . | SP+CD34−CD38− . | |||
|---|---|---|---|---|---|---|---|
| No. abnormal/no. analyzed . | Abnormal (%) . | No. abnormal/no. analyzed . | Abnormal (%) . | No. abnormal/no. analyzed . | Abnormal (%) . | ||
| 1 | inv 16 (72.9) | 0/139 | 0 | 7/29 | 24 | 7/7 | 100 |
| 2 | +8 (100) | 30/30 | 100 | 29/37 | 78.4 | 11/19 | 58 |
| 3 | inv 16 (73) | 0/20 | 0 | 10/16 | 62.5 | 5/5 | 100 |
| 4 | +8 (97.7) | 0/10 | 0 | 7/9 | 78 | 14/117 | 12 |
| 5 | +8 (6) | 5/50 | 10 | 5/47 | 10.6 | 5/21 | 24 |
| 6 | +8 (54.7) | 0/46 | 0 | 4/110 | 3.6 | 2/29 | 7 |
| 7 | +13 (44.5) | 0/15 | 0 | 8/26 | 31 | 15/37 | 41 |
| 8 | +8 (90.4) | 3/9 | 33.3 | 5/26 | 19.2 | 29/39 | 74 |
| 9 | +8 (97.5) | 2/13 | 15.4 | 60/60 | 100 | 4/13 | 31 |
| 10 | inv 16 (93) | 5/57 | 8.8 | 46/57 | 80.7 | NS | NS |
| 11 | inv 16 (84.6) | 0/20 | 0 | 25/28 | 89.3 | 16/16 | 100 |
| 12 | inv 16 (94) | 2/16 | 12.5 | 30/33 | 91 | 9/31 | 29 |
| 13 | del(11)(q14q25)(100) | 0/31 | 0 | 47/74 | 63.5 | 50/50 | 100 |
| 14 | +8 (74) | NS | NS | NS | NS | NS | NS |
| 15 | inv 16 (83) | 0/36 | 0 | 9/36 | 25 | 8/20 | 40 |
| 16 | t(6;11)(q27;q23)(100) | 0/33 | 0 | 29/50 | 58 | 37/37 | 100 |
| Patient . | Cytogenetic marker at diagnosis (% abnormal)3-150 . | SP+CD34+CD38− . | SP−CD34+CD38− . | SP+CD34−CD38− . | |||
|---|---|---|---|---|---|---|---|
| No. abnormal/no. analyzed . | Abnormal (%) . | No. abnormal/no. analyzed . | Abnormal (%) . | No. abnormal/no. analyzed . | Abnormal (%) . | ||
| 1 | inv 16 (72.9) | 0/139 | 0 | 7/29 | 24 | 7/7 | 100 |
| 2 | +8 (100) | 30/30 | 100 | 29/37 | 78.4 | 11/19 | 58 |
| 3 | inv 16 (73) | 0/20 | 0 | 10/16 | 62.5 | 5/5 | 100 |
| 4 | +8 (97.7) | 0/10 | 0 | 7/9 | 78 | 14/117 | 12 |
| 5 | +8 (6) | 5/50 | 10 | 5/47 | 10.6 | 5/21 | 24 |
| 6 | +8 (54.7) | 0/46 | 0 | 4/110 | 3.6 | 2/29 | 7 |
| 7 | +13 (44.5) | 0/15 | 0 | 8/26 | 31 | 15/37 | 41 |
| 8 | +8 (90.4) | 3/9 | 33.3 | 5/26 | 19.2 | 29/39 | 74 |
| 9 | +8 (97.5) | 2/13 | 15.4 | 60/60 | 100 | 4/13 | 31 |
| 10 | inv 16 (93) | 5/57 | 8.8 | 46/57 | 80.7 | NS | NS |
| 11 | inv 16 (84.6) | 0/20 | 0 | 25/28 | 89.3 | 16/16 | 100 |
| 12 | inv 16 (94) | 2/16 | 12.5 | 30/33 | 91 | 9/31 | 29 |
| 13 | del(11)(q14q25)(100) | 0/31 | 0 | 47/74 | 63.5 | 50/50 | 100 |
| 14 | +8 (74) | NS | NS | NS | NS | NS | NS |
| 15 | inv 16 (83) | 0/36 | 0 | 9/36 | 25 | 8/20 | 40 |
| 16 | t(6;11)(q27;q23)(100) | 0/33 | 0 | 29/50 | 58 | 37/37 | 100 |
NS indicates FISH analysis was unsuccessful. See Table 2 for other abbreviations.
As determined on unsorted samples by FISH.