Patient characteristics
| Patient . | Age . | Sex . | Material . | FAB . | WBC (% blasts) (× 109/L) . | Marrow cytogenetics (% abnormal) . |
|---|---|---|---|---|---|---|
| 1 | 48 | M | BM | M4Eo | 101 (71) | 46 XY inv(16)(p13q22)(100) |
| 2 | 77 | M | BM | M2 | 56 (53) | 47 XY, +8, t(12;22); del 20q 8(100) |
| 3 | 36 | M | BM | M4Eo | 85 (90) | 47 XY, inv(16)(p13q22) +22 (100) |
| 4 | 59 | M | PB | M5b | 42 (45) | 48 XY +21 +8 (+1q)(100) |
| 5 | 62 | M | BM | M4 | 14.2 (20) | 48 XY, +8, +20 (12) |
| 6 | 68 | M | BM | RAEB-IT | 63.2 (5) | 48 XY, +8+8 (12) |
| 7 | 58 | F | PB | M4 | 370 (47) | 47 XX, +13 (38) |
| 8 | 46 | M | BM | M5a | 41.3 (5) | 48 XY, +8, +13 (100) |
| 9 | 71 | M | BM | M1 | 10.7 (75) | 47 XY, +8 (100) |
| 10 | 59 | M | BM | M4Eo | 76.1 (91) | 46 XY, inv(16)(p13q22)(93) |
| 11 | 25 | F | PB | M4Eo | 19.6 (9.8) | 46 XX, inv(16)(p13q22)(80) |
| 12 | 68 | M | PB | M4Eo | 27.4 (24) | 45 X-Y, inv(16)(p13q22)(79) |
| 46X-Y, +8, inv(16)(p13q22)(14) | ||||||
| 13 | 74 | F | BM | M 5 | 260 (90) | 46 XX del(11)(q14q25)(100) |
| 14 | 72 | F | BM | M5b | 51 (65) | 47 XX +8 (74) |
| 15 | 30 | M | PB | M4Eo | 47.2 (72) | 46 XY inv(16)(p13q22)(83) |
| 16 | 21 | M | PB | M1 | 320 (90) | 46 XY, add (6) (p23), t(6;11)(q27;q23)(100) |
| Patient . | Age . | Sex . | Material . | FAB . | WBC (% blasts) (× 109/L) . | Marrow cytogenetics (% abnormal) . |
|---|---|---|---|---|---|---|
| 1 | 48 | M | BM | M4Eo | 101 (71) | 46 XY inv(16)(p13q22)(100) |
| 2 | 77 | M | BM | M2 | 56 (53) | 47 XY, +8, t(12;22); del 20q 8(100) |
| 3 | 36 | M | BM | M4Eo | 85 (90) | 47 XY, inv(16)(p13q22) +22 (100) |
| 4 | 59 | M | PB | M5b | 42 (45) | 48 XY +21 +8 (+1q)(100) |
| 5 | 62 | M | BM | M4 | 14.2 (20) | 48 XY, +8, +20 (12) |
| 6 | 68 | M | BM | RAEB-IT | 63.2 (5) | 48 XY, +8+8 (12) |
| 7 | 58 | F | PB | M4 | 370 (47) | 47 XX, +13 (38) |
| 8 | 46 | M | BM | M5a | 41.3 (5) | 48 XY, +8, +13 (100) |
| 9 | 71 | M | BM | M1 | 10.7 (75) | 47 XY, +8 (100) |
| 10 | 59 | M | BM | M4Eo | 76.1 (91) | 46 XY, inv(16)(p13q22)(93) |
| 11 | 25 | F | PB | M4Eo | 19.6 (9.8) | 46 XX, inv(16)(p13q22)(80) |
| 12 | 68 | M | PB | M4Eo | 27.4 (24) | 45 X-Y, inv(16)(p13q22)(79) |
| 46X-Y, +8, inv(16)(p13q22)(14) | ||||||
| 13 | 74 | F | BM | M 5 | 260 (90) | 46 XX del(11)(q14q25)(100) |
| 14 | 72 | F | BM | M5b | 51 (65) | 47 XX +8 (74) |
| 15 | 30 | M | PB | M4Eo | 47.2 (72) | 46 XY inv(16)(p13q22)(83) |
| 16 | 21 | M | PB | M1 | 320 (90) | 46 XY, add (6) (p23), t(6;11)(q27;q23)(100) |
BM indicates bone marrow; PB, peripheral blood; FAB, French-American-British group; WBC, white blood cell; RAEB-IT, refractory anemia with excess of blasts in transformation.