Key hematology parameters in CD59−/−, CD59+/−, and CD59+/+ mice
| . | Hb (g/dL) . | RBC (1012/L) . | WBC (109/L) . | Plts (109/L) . | Retics (109/L) . | Retics (%) . |
|---|---|---|---|---|---|---|
| Study 1 (n = 5 in each group) | ||||||
| CD59−/− | 14.20 (0.97) | 9.28 (0.56) | 1.89 (1.21) | 997 (102) | 472 (85.7)* | 5.14 (1.25)* |
| CD59+/− | 14.00 (0.53) | 9.28 (0.27) | 2.39 (0.89) | 985 (223) | 294 (64.3) | 3.16 (0.63) |
| CD59+/+ | 14.48 (0.33) | 9.48 (0.42) | 3.58 (1.52) | 1029 (216) | 290 (22.4) | 3.06 (0.23) |
| Study 2 (n = 10 in each group) | ||||||
| CD59−/− | 14.90 (0.77) | 9.78 (0.49) | 4.76 (2.65) | 1071 (150) | 448 (53.4)* | 4.58 (0.48)* |
| CD59+/+ | 14.60 (0.51) | 9.85 (0.35) | 4.83 (2.19) | 1210 (236) | 338 (39.7) | 3.43 (0.33) |
| . | Hb (g/dL) . | RBC (1012/L) . | WBC (109/L) . | Plts (109/L) . | Retics (109/L) . | Retics (%) . |
|---|---|---|---|---|---|---|
| Study 1 (n = 5 in each group) | ||||||
| CD59−/− | 14.20 (0.97) | 9.28 (0.56) | 1.89 (1.21) | 997 (102) | 472 (85.7)* | 5.14 (1.25)* |
| CD59+/− | 14.00 (0.53) | 9.28 (0.27) | 2.39 (0.89) | 985 (223) | 294 (64.3) | 3.16 (0.63) |
| CD59+/+ | 14.48 (0.33) | 9.48 (0.42) | 3.58 (1.52) | 1029 (216) | 290 (22.4) | 3.06 (0.23) |
| Study 2 (n = 10 in each group) | ||||||
| CD59−/− | 14.90 (0.77) | 9.78 (0.49) | 4.76 (2.65) | 1071 (150) | 448 (53.4)* | 4.58 (0.48)* |
| CD59+/+ | 14.60 (0.51) | 9.85 (0.35) | 4.83 (2.19) | 1210 (236) | 338 (39.7) | 3.43 (0.33) |
Hb, hemoglobin; RBC, red blood cell count; WBC, white blood cell count; Plts, platelets; Retics, reticulocytes. Numbers in brackets are SDs. The mice in study 1 were 10-week-old littermates (mixed sexes), and in study 2 they were 20-week-old littermates (all male).
Significant differences (P < .01 toP < .001) when compared with same parameter in other group(s) in study.