Patient characteristics and outcomes
| Patient . | Age (y) . | Sex . | Disease status at study entry . | No. arsenic cycles . | Best response . | Outcome (posttreatment follow-up) . |
|---|---|---|---|---|---|---|
| 1* | 35 | M | Fourth relapse | 4 | Cyto, PCR | Dead, relapsed disease (3 mo) |
| 2 | 71 | M | First relapse (CNS) | 3 | Cyto, PCR | Dead, relapsed disease (21 mo) |
| 3 | 34 | M | First relapse | <1 | N/E | Sudden death, d15, cycle 1 |
| 4 | 23 | M | First relapse | 1 | Cyto, PCR | Allogeneic transplant Dead, relapsed disease (13 mo) |
| 5 | 55 | M | First relapse | 3 | Cyto | Dead, relapsed disease (3 mo) |
| 6 | 49 | M | First relapse (CNS) | 1 | Cyto, PCR | Allogeneic transplant Dead, relapsed disease (12 mo) |
| 7 | 11 | M | First relapse | 3 | Persistent disease | MUD transplant Dead, VOD (9 mo) |
| 8 | 19 | F | First relapse | 3 | Cyto, PCR | MUD transplant Alive, disease free (8 mo) |
| 9 | 26 | F | First relapse | <1 | N/E | Sudden death, d11, cycle 1 |
| 10 | 37 | F | Third relapse | <1 | N/E | Sudden death, d9, cycle 1 |
| Patient . | Age (y) . | Sex . | Disease status at study entry . | No. arsenic cycles . | Best response . | Outcome (posttreatment follow-up) . |
|---|---|---|---|---|---|---|
| 1* | 35 | M | Fourth relapse | 4 | Cyto, PCR | Dead, relapsed disease (3 mo) |
| 2 | 71 | M | First relapse (CNS) | 3 | Cyto, PCR | Dead, relapsed disease (21 mo) |
| 3 | 34 | M | First relapse | <1 | N/E | Sudden death, d15, cycle 1 |
| 4 | 23 | M | First relapse | 1 | Cyto, PCR | Allogeneic transplant Dead, relapsed disease (13 mo) |
| 5 | 55 | M | First relapse | 3 | Cyto | Dead, relapsed disease (3 mo) |
| 6 | 49 | M | First relapse (CNS) | 1 | Cyto, PCR | Allogeneic transplant Dead, relapsed disease (12 mo) |
| 7 | 11 | M | First relapse | 3 | Persistent disease | MUD transplant Dead, VOD (9 mo) |
| 8 | 19 | F | First relapse | 3 | Cyto, PCR | MUD transplant Alive, disease free (8 mo) |
| 9 | 26 | F | First relapse | <1 | N/E | Sudden death, d11, cycle 1 |
| 10 | 37 | F | Third relapse | <1 | N/E | Sudden death, d9, cycle 1 |
Cyto indicates cytogenetic complete response; PCR, molecular complete response; CNS, central nervous system; N/E, not evaluable; MUD, matched unrelated donor transplant; VOD, veno-occlusive disease.
Single patient exception.