Hematopoietic responses to 21 days of recombinant canine granulocyte-colony stimulating factor treatment after seventh dose of total body irradiation
Hematopoietic parameter . | Elderly dogs median (range) . | Young dogs median (range) . | P . |
---|---|---|---|
Days to maximum ANC | 3 (1-20) | 4.5 (1-20) | .69 |
% increases in ANC | 331 (128-929) | 423 (145-862) | .34 |
Days of ANC elevation | 23 (27-43) | 16.5 (6-23) | .69 |
% increase in CFU-GM in blood on day 9 of rcG-CSF | 490 (183-688) | 666.5 (334-1010) | .20 |
% declines in PLT counts3-150 | 74 (43-94) | 89 (77-94) | .11 |
Hematopoietic parameter . | Elderly dogs median (range) . | Young dogs median (range) . | P . |
---|---|---|---|
Days to maximum ANC | 3 (1-20) | 4.5 (1-20) | .69 |
% increases in ANC | 331 (128-929) | 423 (145-862) | .34 |
Days of ANC elevation | 23 (27-43) | 16.5 (6-23) | .69 |
% increase in CFU-GM in blood on day 9 of rcG-CSF | 490 (183-688) | 666.5 (334-1010) | .20 |
% declines in PLT counts3-150 | 74 (43-94) | 89 (77-94) | .11 |
CFU-GM indicates granulocyte-macrophage colony forming unit; rcG-CSF, recombinant canine granulocyte-colony stimulating factor. See Tables 1 and 2 for other abbreviations.
% of PLT count obtained before the last TBI dose and G-CSF treatment.