Table 2.

Release of tumor necrosis factor α from monocytes cultured for 24 hours with lipopolysaccharide (5 μg/mL), according to subject group

Subject groupTNF-α (ng/L)
Controls (n = 34)* 478.5 ± 150.7 
Patients with HHC (n = 50) 385.2 ± 193.4  
C282Y +/+ patients (n = 32) 363.4 ± 157.9† 
Non-C282Y +/+ patients (n = 18) 424.0 ± 244.6 
Subject groupTNF-α (ng/L)
Controls (n = 34)* 478.5 ± 150.7 
Patients with HHC (n = 50) 385.2 ± 193.4  
C282Y +/+ patients (n = 32) 363.4 ± 157.9† 
Non-C282Y +/+ patients (n = 18) 424.0 ± 244.6 

Values are mean ± SD.

TNF-α indicates tumor necrosis factor α; HHC, hereditary hemochromatosis.

*

Two controls were C282Y +/−, and none were C282Y +/+ or had compound heterozygosity.

†

P = .01 compared with controls.

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