Table 1.
 |
|
ND, not determined; N/A, not applicable.
*
KMM-1 MM cell line and intramedullary MM primary tumor samples; FISH analyses on interphase nuclei only for P26 and P46, but metaphase chromosomes and interphase nuclei for all other samples.
†
Variant t(6;22)(p21;q11) translocation.
‡
Type/number of t(6;14)(p21;q32) or t(6;22)(p21;q11) derivatives, with the presence (+) or absence (0) of hybridization signals noted in next 4 columns.
F1-153
CD3 BAC has cyclin D3 and chromosome 6 KMM1 breakpoint sequences; shaded boxes indicate tumors for which this probe identifies both the der(6) and der(14) derivatives.
F1-155
Cyclin D3 cosmid and BAC probes are at t(6;14) breakpoint, but CH probe is separated from breakpoint (see “Detection of t(6;14)(p21;q32) in primary MM tumors”).