Table 1.

Representative sample of very highly abundant named genes in human and baboon CD34+ cells, by functional category

UniGene cluster ID
GenBank
accession no.
DescriptionGene name
Growth factors/cytokines    
 Hs.56023 AA262988 Brain-derived neurotrophic factor BDNF 
 Hs.180577 AA496452 Granulin GRN 
 Hs.251664 N54596 Insulin-like growth factor 2 IGF2 
 Hs.82045 AA968896 Midkine MDK 
 Hs.118787 AA633901 Transforming growth factor, β induced TGFBI  
Cell surface/receptors    
 Hs.85258 AA443649 CD8 antigen, alpha polypeptide CD8A 
 Hs.75626 AA136359 CD58 antigen CD58 
 Hs.75564 AA456183 CD151 antigen CD151 
 Hs.2175 AA443000 Colony stimulating factor 3 precursor receptor CSF3R 
 Hs.110849 AA098896 Estrogen-related receptor α ESRRA 
 Hs.89650 R68805 Integral transmembrane protein 1 ITM1 
 Hs.1724 AA903183 Interleukin 2 receptor, α IL2RA  
 Hs.172689 W44701 Interleukin 3 receptor, α IL3RA  
 Hs.47860 N63949 Neurotrophic tyrosine kinase, receptor, type 2 NTRK2 
 Hs.82028 AA487034 Transforming growth factor, β receptor II TGFBR2  
Intracellular signaling molecules    
 Hs.166154 AA463972 Jagged 2 JAG2  
 Hs.86859 H53703 Growth factor receptor-bound protein 7 GRB7  
 Hs.78793 AA447574 Protein kinase C, ζ PRKCZ  
 Hs.62402 AA890663 p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20 related) PAK1 
 Hs.75074 AA455056 Mitogen-activated protein kinase–activated protein kinase 2 MAPKAPK2 
 Hs.73799 AA409256 Guanine nucleotide binding protein, α inhibiting activity GNAI3 
 Hs.75217 AA293050 Mitogen-activated protein kinase kinase 4 MAP2K4  
 Hs.138860 AA443506 Rho GTPase activating protein 1 ARHGAP1  
Cell cycle proteins    
 Hs.82906 AA464698 Cell division cycle 20, S. cerevisiae homolog CDC20  
 Hs.153752 AA448659 Cell division cycle 25B CDC25B  
 Hs.172405 T81764 Cell division cycle 27 CDC27  
 Hs.77550 AA459292 CDC28 protein kinase 1 CKS1  
Apoptosis/antiapoptosis factors    
 Hs.82890 AA455281 Defender against cell death 1 DAD1  
 Hs.227817 AA459263 BCL-2–related protein A1 BCL2A1  
Cytoskeleton/cell matrix/adhesion    
 Hs.183805 AA464755 Ankyrin 1, erythrocytic ANK1  
 Hs.171271 AA442092 Catenin, β 1 CTNNB1  
 Hs.75617 AA430540 Collagen, type IV, α 2 COL4A2  
 Hs.71346 AA400329 Neurofilament 3 (150 kd medium) NEF3  
 Hs.78146 R22412 Platelet/endothelial cell adhesion molecule PECAM1 
 Hs.75318 AA180912 Tubulin, α 1 TUBA1  
Metabolic proteins    
 Hs.278399 AA844818 Amylase, α 2A; pancreatic AMY2A  
 Hs.155097 H23187 Carbonic anhydrase II CA2  
 Hs.81097 AA862813 Cytochrome c oxidase subunit VIII COX8  
 Hs.172690 AA456900 Diacylglycerol kinase alpha DGKA  
 Hs.944 AA401111 Glucose phosphate isomerase GPI  
 Hs.2795 AA489611 Lactate dehydrogenase A LDHA  
Transcription factors/activators/inhibitors    
 Hs.158195 AA250730 Heat shock transcription factor 2 HSF2 
 Hs.22554 AA252627 Homeobox B5 HOXB5 
 Hs.153837 N29376 Myeloid cell nuclear differentiation antigen MNDA  
 Hs.79334 AA633811 Nuclear factor, interleukin 3 regulated NFIL3 
 Hs.74002 AA495962 Nuclear receptor coactivator 1 NCOA1 
 Hs.192861 N71628 Spi-B transcription factor SPI-B  
 Hs.3005 AA284693 Transcription factor AP-4 TFAP4 
UniGene cluster ID
GenBank
accession no.
DescriptionGene name
Growth factors/cytokines    
 Hs.56023 AA262988 Brain-derived neurotrophic factor BDNF 
 Hs.180577 AA496452 Granulin GRN 
 Hs.251664 N54596 Insulin-like growth factor 2 IGF2 
 Hs.82045 AA968896 Midkine MDK 
 Hs.118787 AA633901 Transforming growth factor, β induced TGFBI  
Cell surface/receptors    
 Hs.85258 AA443649 CD8 antigen, alpha polypeptide CD8A 
 Hs.75626 AA136359 CD58 antigen CD58 
 Hs.75564 AA456183 CD151 antigen CD151 
 Hs.2175 AA443000 Colony stimulating factor 3 precursor receptor CSF3R 
 Hs.110849 AA098896 Estrogen-related receptor α ESRRA 
 Hs.89650 R68805 Integral transmembrane protein 1 ITM1 
 Hs.1724 AA903183 Interleukin 2 receptor, α IL2RA  
 Hs.172689 W44701 Interleukin 3 receptor, α IL3RA  
 Hs.47860 N63949 Neurotrophic tyrosine kinase, receptor, type 2 NTRK2 
 Hs.82028 AA487034 Transforming growth factor, β receptor II TGFBR2  
Intracellular signaling molecules    
 Hs.166154 AA463972 Jagged 2 JAG2  
 Hs.86859 H53703 Growth factor receptor-bound protein 7 GRB7  
 Hs.78793 AA447574 Protein kinase C, ζ PRKCZ  
 Hs.62402 AA890663 p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20 related) PAK1 
 Hs.75074 AA455056 Mitogen-activated protein kinase–activated protein kinase 2 MAPKAPK2 
 Hs.73799 AA409256 Guanine nucleotide binding protein, α inhibiting activity GNAI3 
 Hs.75217 AA293050 Mitogen-activated protein kinase kinase 4 MAP2K4  
 Hs.138860 AA443506 Rho GTPase activating protein 1 ARHGAP1  
Cell cycle proteins    
 Hs.82906 AA464698 Cell division cycle 20, S. cerevisiae homolog CDC20  
 Hs.153752 AA448659 Cell division cycle 25B CDC25B  
 Hs.172405 T81764 Cell division cycle 27 CDC27  
 Hs.77550 AA459292 CDC28 protein kinase 1 CKS1  
Apoptosis/antiapoptosis factors    
 Hs.82890 AA455281 Defender against cell death 1 DAD1  
 Hs.227817 AA459263 BCL-2–related protein A1 BCL2A1  
Cytoskeleton/cell matrix/adhesion    
 Hs.183805 AA464755 Ankyrin 1, erythrocytic ANK1  
 Hs.171271 AA442092 Catenin, β 1 CTNNB1  
 Hs.75617 AA430540 Collagen, type IV, α 2 COL4A2  
 Hs.71346 AA400329 Neurofilament 3 (150 kd medium) NEF3  
 Hs.78146 R22412 Platelet/endothelial cell adhesion molecule PECAM1 
 Hs.75318 AA180912 Tubulin, α 1 TUBA1  
Metabolic proteins    
 Hs.278399 AA844818 Amylase, α 2A; pancreatic AMY2A  
 Hs.155097 H23187 Carbonic anhydrase II CA2  
 Hs.81097 AA862813 Cytochrome c oxidase subunit VIII COX8  
 Hs.172690 AA456900 Diacylglycerol kinase alpha DGKA  
 Hs.944 AA401111 Glucose phosphate isomerase GPI  
 Hs.2795 AA489611 Lactate dehydrogenase A LDHA  
Transcription factors/activators/inhibitors    
 Hs.158195 AA250730 Heat shock transcription factor 2 HSF2 
 Hs.22554 AA252627 Homeobox B5 HOXB5 
 Hs.153837 N29376 Myeloid cell nuclear differentiation antigen MNDA  
 Hs.79334 AA633811 Nuclear factor, interleukin 3 regulated NFIL3 
 Hs.74002 AA495962 Nuclear receptor coactivator 1 NCOA1 
 Hs.192861 N71628 Spi-B transcription factor SPI-B  
 Hs.3005 AA284693 Transcription factor AP-4 TFAP4 

Genes highlighted in bold are known to be expressed in hematopoietic tissues. The GenBank accession number specifies the identification of the IMAGE clone present on the GeneFilter membrane, while the description refers to the entire UniGene cluster to which this clone belongs.

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