Table 5.

Relative restoration of F4/80+ tissue macrophage development by colony-stimulating factor 1 injection and by TgC expression

F4/80+ tissue  macrophages  CSF-1 requirementResponse ofCsf1op/Csf1op
mouse to postnatal injection of CSF-1
Response ofCsf1op/Csf1op mouse to Tgc
Muscle Complete None Complete 
Tendon Complete None Complete 
Periosteum Complete None Complete 
Synovium Complete None Complete 
Dermis Complete Partial/none Complete 
Kidney Complete Complete Complete 
Testes Complete Complete Complete  
Adrenal gland Partial None Complete 
Bladder Partial Partial Partial 
Stomach Partial Partial Complete  
Small intestine Partial Partial Complete  
Sublingual salivary gland Partial Partial Complete 
Liver Partial Complete Complete 
Spleen Partial Complete Complete 
Thymus Partial None Complete 
Epidermis None None None  
Lymph node None None None  
Bone marrow monocyte None None None 
F4/80+ tissue  macrophages  CSF-1 requirementResponse ofCsf1op/Csf1op
mouse to postnatal injection of CSF-1
Response ofCsf1op/Csf1op mouse to Tgc
Muscle Complete None Complete 
Tendon Complete None Complete 
Periosteum Complete None Complete 
Synovium Complete None Complete 
Dermis Complete Partial/none Complete 
Kidney Complete Complete Complete 
Testes Complete Complete Complete  
Adrenal gland Partial None Complete 
Bladder Partial Partial Partial 
Stomach Partial Partial Complete  
Small intestine Partial Partial Complete  
Sublingual salivary gland Partial Partial Complete 
Liver Partial Complete Complete 
Spleen Partial Complete Complete 
Thymus Partial None Complete 
Epidermis None None None  
Lymph node None None None  
Bone marrow monocyte None None None 

CSF-1 indicates colony-stimulating factor 1.

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