Table 2. T-cell proliferation and in... | American Society of Hematology

Table 2.

T-cell proliferation and in vitro anti–GPIIb-IIIa antibody production in response to recombinant GPIIb-IIIa fragments

Healthy donors	Age/sex	Fragment-induced T-cell proliferation (SI)^*						Anti–GPIIb-IIIa antibody (OD₄₅₀)
Healthy donors	Age/sex	IIbα18-259	IIbα244-575	IIbα566-841	IIIa22-262	IIIa254-462	IIIa708-762	GST	IIbα18-259	IIbα244-575	IIbα566-841	IIIa22-262	IIIa254-462	IIIa708-762
HD1	37/M	3.03	4.17	—	—	3.71	—	0.002	0.003	0.000	0.001	0.003	0.002	0.005
HD2	38/F	—	—	3.17	4.19	—	—	NT
HD3	23/F	—	—	3.21	—	3.93	—	0.005	0.000	0.006	0.002	0.002	0.000	0.004
HD4	22/M	—	4.11	—	6.31	—	—	0.001	0.005	0.007	0.000	0.003	0.012	0.001
HD5	44/M	—	3.33	—	—	—	5.61	0.011	0.013	0.001	0.004	0.004	0.007	0.005
HD6	47/F	—	—	4.07	—	5.00	—	NT
HD7	32/M	3.96	—	4.01	—	—	5.94	0.000	0.000	0.003	0.002	0.000	0.005	0.001
HD8	28/F	—	—	3.78	3.44	—	—	0.003	0.005	0.000	0.003	0.000	0.007	0.002
HD9	56/F	—	3.94	6.50	—	—	—	0.003	0.008	0.009	0.001	0.003	0.000	0.003
HD10	40/F	4.88	—	—	—	4.36	—	NT

Healthy donors	Age/sex	Fragment-induced T-cell proliferation (SI)^*						Anti–GPIIb-IIIa antibody (OD₄₅₀)
Healthy donors	Age/sex	IIbα18-259	IIbα244-575	IIbα566-841	IIIa22-262	IIIa254-462	IIIa708-762	GST	IIbα18-259	IIbα244-575	IIbα566-841	IIIa22-262	IIIa254-462	IIIa708-762
HD1	37/M	3.03	4.17	—	—	3.71	—	0.002	0.003	0.000	0.001	0.003	0.002	0.005
HD2	38/F	—	—	3.17	4.19	—	—	NT
HD3	23/F	—	—	3.21	—	3.93	—	0.005	0.000	0.006	0.002	0.002	0.000	0.004
HD4	22/M	—	4.11	—	6.31	—	—	0.001	0.005	0.007	0.000	0.003	0.012	0.001
HD5	44/M	—	3.33	—	—	—	5.61	0.011	0.013	0.001	0.004	0.004	0.007	0.005
HD6	47/F	—	—	4.07	—	5.00	—	NT
HD7	32/M	3.96	—	4.01	—	—	5.94	0.000	0.000	0.003	0.002	0.000	0.005	0.001
HD8	28/F	—	—	3.78	3.44	—	—	0.003	0.005	0.000	0.003	0.000	0.007	0.002
HD9	56/F	—	3.94	6.50	—	—	—	0.003	0.008	0.009	0.001	0.003	0.000	0.003
HD10	40/F	4.88	—	—	—	4.36	—	NT

See Table 1 for abbreviations.

Negative results (SI < 3) are indicated by dashes.