Table 1.

Ki values of MMP inhibitors used in this study

BB94RS-11RS-16
MMP-1 0.4 70 110 
MMP-13 0.53 0.17 0.87  
MMP-2 0.15 0.054 0.11 
MMP-9 0.46 0.065 0.66  
MMP-3 2.3 5.2 2.6 
MMP-7 0.44 240 570 
MMP-12 0.33 0.033 ND 
TACE 150* > 10 000* 94* 
BB94RS-11RS-16
MMP-1 0.4 70 110 
MMP-13 0.53 0.17 0.87  
MMP-2 0.15 0.054 0.11 
MMP-9 0.46 0.065 0.66  
MMP-3 2.3 5.2 2.6 
MMP-7 0.44 240 570 
MMP-12 0.33 0.033 ND 
TACE 150* > 10 000* 94* 

The Ki values are determined as described in “Materials and methods” and are expressed in nM.

ND indicates not determined.

*

Cell-based assay, not comparable with the Kivalues of the other MMPs.

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