Genetic and allelic frequencies of FV Leiden, prothrombin 20210A/G, FVII-323 Del/Ins, and FXIII V34L polymorphisms in patients, controls, and general population
| . | FV Leiden . | Prothrombin 20210 . | FVII-323 . | FXIII V34L . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ± N (%) . | −/− N . | + Freq . | A/G N (%) . | G/G N . | A Freq . | D/I + I/I N (%) . | D/D N . | I Freq . | V/L + L/L N (%) . | V/V N . | L Freq . | |
| PIH (N = 141) | 1 (0.7) | 140 | 0.004 | 3 (2.1) | 138 | 0.011 | 40 + 2 (29.8) | 99 | 0.156 | 41 + 8 (34.8) | 92 | 0.202 |
| SAH (N = 60) | 1 (1.7) | 59 | 0.008 | 0 | 60 | 0 | 14 + 3 (28.3) | 43 | 0.167 | 17 + 7 (40.0) | 36 | 0.258 |
| Total (N = 201) | 2 (1.0) | 199 | 0.005 | 3 (1.5) | 198 | 0.007 | 54 + 5 (29.4) | 142 | 0.159 | 58 + 15 (36.3) | 128 | 0.219 |
| Control (N = 201) | 10 (4.9) | 191 | 0.025 | 6 (3.0) | 195 | 0.015 | 36 + 4 (19.9) | 161 | 0.109 | 64 + 6 (34.8) | 131 | 0.189 |
| P | .019 | .020 | .312 | .315 | .028 | .039 | .755 | .294 | ||||
| OR | 0.19 | 0.20 | 0.49 | 0.50 | 1.54 | 1.54 | 1.07 | 1.20 | ||||
| 95% CI | 0.03-0.95 | 0.03-0.96 | 0.10-2.25 | 0.10-2.24 | 1.03-2.72 | 1.0-2.37 | 0.69-1.64 | 0.84-1.72 | ||||
| GP (N = 490) | 19 (3.9) | 471 | 0.019 | 11 (2.3) | 479 | 0.011 | 99 + 6 (21.4) | 385 | 0.112 | 159 + 15 (35.6) | 316 | 0.193 |
| . | FV Leiden . | Prothrombin 20210 . | FVII-323 . | FXIII V34L . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ± N (%) . | −/− N . | + Freq . | A/G N (%) . | G/G N . | A Freq . | D/I + I/I N (%) . | D/D N . | I Freq . | V/L + L/L N (%) . | V/V N . | L Freq . | |
| PIH (N = 141) | 1 (0.7) | 140 | 0.004 | 3 (2.1) | 138 | 0.011 | 40 + 2 (29.8) | 99 | 0.156 | 41 + 8 (34.8) | 92 | 0.202 |
| SAH (N = 60) | 1 (1.7) | 59 | 0.008 | 0 | 60 | 0 | 14 + 3 (28.3) | 43 | 0.167 | 17 + 7 (40.0) | 36 | 0.258 |
| Total (N = 201) | 2 (1.0) | 199 | 0.005 | 3 (1.5) | 198 | 0.007 | 54 + 5 (29.4) | 142 | 0.159 | 58 + 15 (36.3) | 128 | 0.219 |
| Control (N = 201) | 10 (4.9) | 191 | 0.025 | 6 (3.0) | 195 | 0.015 | 36 + 4 (19.9) | 161 | 0.109 | 64 + 6 (34.8) | 131 | 0.189 |
| P | .019 | .020 | .312 | .315 | .028 | .039 | .755 | .294 | ||||
| OR | 0.19 | 0.20 | 0.49 | 0.50 | 1.54 | 1.54 | 1.07 | 1.20 | ||||
| 95% CI | 0.03-0.95 | 0.03-0.96 | 0.10-2.25 | 0.10-2.24 | 1.03-2.72 | 1.0-2.37 | 0.69-1.64 | 0.84-1.72 | ||||
| GP (N = 490) | 19 (3.9) | 471 | 0.019 | 11 (2.3) | 479 | 0.011 | 99 + 6 (21.4) | 385 | 0.112 | 159 + 15 (35.6) | 316 | 0.193 |
PIH, primary intracerebral hemorrhage; SAH, subarachnoid hemorrhage; OR, odds ratio; CI, confidence interval; Freq, frequency; GP, general population.