VH gene segments on chromosome 14q32.2
| Type of VH gene segment . | No. segments in VH families . | Total . | |||||
|---|---|---|---|---|---|---|---|
| VH1/VH7 . | VH2 . | VH3 . | VH4 . | VH5 . | VH6 . | ||
| Total germline segments (rows A, B, C) | 19 | 4 | 65 | 32 | 2 | 1 | 123 |
| (%) | (15.4) | (3.3) | (52.8) | (26.0) | (1.6) | (0.8) | |
| Rearrangable (rows A + B) | 14 | 4 | 27 | 8 | 1 | 1 | 55 |
| (%) | (25.5) | (7.3) | (49.1) | (14.5) | (1.8) | (1.8) | |
| A) Functional | 10 | 3 | 20 | 7 | 1 | 1 | 42 |
| (%) | (23.8) | (7.1) | (47.6) | (16.7) | (2.4) | (2.4) | |
| Functional protein equivalent found | 9 | 3 | 19 | 6 | 1 | 1 | |
| Transcribed mRNA equivalent found | — | — | — | 1 | — | — | |
| Other VH with ORF, intact promoter, and RSS | 1 | — | 1 | — | — | — | |
| B) Pseudogenes with intact promoter and RSS | 4 | 1 | 7 | 1 | — | — | 13 |
| C) Nonrearrangeable pseudogenes | 5 | — | 38 | 24 | 1 | — | 68 |
| Type of VH gene segment . | No. segments in VH families . | Total . | |||||
|---|---|---|---|---|---|---|---|
| VH1/VH7 . | VH2 . | VH3 . | VH4 . | VH5 . | VH6 . | ||
| Total germline segments (rows A, B, C) | 19 | 4 | 65 | 32 | 2 | 1 | 123 |
| (%) | (15.4) | (3.3) | (52.8) | (26.0) | (1.6) | (0.8) | |
| Rearrangable (rows A + B) | 14 | 4 | 27 | 8 | 1 | 1 | 55 |
| (%) | (25.5) | (7.3) | (49.1) | (14.5) | (1.8) | (1.8) | |
| A) Functional | 10 | 3 | 20 | 7 | 1 | 1 | 42 |
| (%) | (23.8) | (7.1) | (47.6) | (16.7) | (2.4) | (2.4) | |
| Functional protein equivalent found | 9 | 3 | 19 | 6 | 1 | 1 | |
| Transcribed mRNA equivalent found | — | — | — | 1 | — | — | |
| Other VH with ORF, intact promoter, and RSS | 1 | — | 1 | — | — | — | |
| B) Pseudogenes with intact promoter and RSS | 4 | 1 | 7 | 1 | — | — | 13 |
| C) Nonrearrangeable pseudogenes | 5 | — | 38 | 24 | 1 | — | 68 |
Based on Matsuda et al.4
mRNA indicates messenger RNA; ORF, open-reading frames; RSS, recombination signal sequence.