Characterization of 33 cloned restriction landmark genomic scanning loci methylated in acute myeloid leukemia diagnosis samples
| Master profile address . | Homology . | Genbank accession no. . | Identity . | Total loss events . | Chromosome . | CpG island characteristics? . | Leukemia-specific clone? . |
|---|---|---|---|---|---|---|---|
| 2C40 | gene | L12397 | Dopamine D4 receptor | 11 | 11p15.5 | Y | Y |
| 2C58 | EST | Al221816 | — | 10 | — | Y | N |
| *5C08 | EST | BE741583 | — | 7 | 11q | Y | N |
| 2D48 | PAC | 2822164 | — | 5 | 7p15-21 | Y | N |
| 2D63 | none | — | — | 6 | — | N | N |
| 3B36 | gene | U56438 | CYP1B1 | 5 | 2p21-22 | Y | N |
| *3C01 | gene | U55180 | G-α-olfactory | 4 | 18p11.21 | Y | N |
| *4D50 | EST | BF308382 | — | 4 | 16 | Y | N |
| *2C24 | EST | BF511664 | — | 3 | 3p | Y | N |
| 2C35 | BAC | AL139281 | — | 3 | 10p12 | Y | N |
| 2E24 | gene | XM009979.1 | monocarboxylate transporter 3 | 3 | 22q12.3-13.2 | Y | N |
| 3D35 | gene | AL035694 | Tbx18 | 3 | 6q14.1-15 | Y | N |
| *3D41 | EST | Al433656 | — | 3 | 12 | Y | N |
| 3E55 | gene | NM000209 | Insulin promoter factor 1 | 3 | 13q12.1 | Y | N |
| 4E53 | BAC | AL353195 | — | 3 | 13 | Y | Y |
| 2D55 | BAC | AF205588 | — | 2 | 10 | Y | N |
| 2D74 | EST | AW295881 | — | 2 | 3 | Y | N |
| 3D40 | BAC | AC027515 | — | 2 | 18 | Y | N |
| 3F02 | BAC | AL390196 | — | 2 | 6 | N | N |
| 3F50 | BAC | AL357396 | — | 2 | 10 | Y | N |
| 4D07 | EST | AA700990 | — | 2 | 14 | Y | N |
| *4D12 | EST | AA364858 | — | 2 | 11q | Y | N |
| *4D47 | EST | AW297880 | — | 2 | 2 | Y | N |
| 2D10 | BAC | AP001130 | — | 1 | 11q14 | Y | N |
| 2D14 | gene | S87068 | CDβ beta 1 chain | 1 | 2 | Y | Y |
| *2F50 | gene | NM002699 | POU3F1 | 1 | 1p34.1 | Y | N |
| 2G10 | EST | AA772261 | — | 1 | 7 | Y | N |
| 3C64 | BAC | AC073094 | — | 1 | — | Y | N |
| 3D60 | BAC | AL036091 | — | 1 | 1q32.2-32.3 | Y | N |
| 3F16 | BAC | AL354950 | — | 1 | 10 | Y | Y |
| 3F72 | gene | NM022049 | G-protein–coupled receptor 88 | 1 | 1p21.3 | Y | Y |
| 3F82 | gene | XM006914 | Cold shock domain A | 1 | 12p13.1 | Y | N |
| *6E34 | gene | X69950 | WIT1 | 1 | 11p13 | Y | N |
| Master profile address . | Homology . | Genbank accession no. . | Identity . | Total loss events . | Chromosome . | CpG island characteristics? . | Leukemia-specific clone? . |
|---|---|---|---|---|---|---|---|
| 2C40 | gene | L12397 | Dopamine D4 receptor | 11 | 11p15.5 | Y | Y |
| 2C58 | EST | Al221816 | — | 10 | — | Y | N |
| *5C08 | EST | BE741583 | — | 7 | 11q | Y | N |
| 2D48 | PAC | 2822164 | — | 5 | 7p15-21 | Y | N |
| 2D63 | none | — | — | 6 | — | N | N |
| 3B36 | gene | U56438 | CYP1B1 | 5 | 2p21-22 | Y | N |
| *3C01 | gene | U55180 | G-α-olfactory | 4 | 18p11.21 | Y | N |
| *4D50 | EST | BF308382 | — | 4 | 16 | Y | N |
| *2C24 | EST | BF511664 | — | 3 | 3p | Y | N |
| 2C35 | BAC | AL139281 | — | 3 | 10p12 | Y | N |
| 2E24 | gene | XM009979.1 | monocarboxylate transporter 3 | 3 | 22q12.3-13.2 | Y | N |
| 3D35 | gene | AL035694 | Tbx18 | 3 | 6q14.1-15 | Y | N |
| *3D41 | EST | Al433656 | — | 3 | 12 | Y | N |
| 3E55 | gene | NM000209 | Insulin promoter factor 1 | 3 | 13q12.1 | Y | N |
| 4E53 | BAC | AL353195 | — | 3 | 13 | Y | Y |
| 2D55 | BAC | AF205588 | — | 2 | 10 | Y | N |
| 2D74 | EST | AW295881 | — | 2 | 3 | Y | N |
| 3D40 | BAC | AC027515 | — | 2 | 18 | Y | N |
| 3F02 | BAC | AL390196 | — | 2 | 6 | N | N |
| 3F50 | BAC | AL357396 | — | 2 | 10 | Y | N |
| 4D07 | EST | AA700990 | — | 2 | 14 | Y | N |
| *4D12 | EST | AA364858 | — | 2 | 11q | Y | N |
| *4D47 | EST | AW297880 | — | 2 | 2 | Y | N |
| 2D10 | BAC | AP001130 | — | 1 | 11q14 | Y | N |
| 2D14 | gene | S87068 | CDβ beta 1 chain | 1 | 2 | Y | Y |
| *2F50 | gene | NM002699 | POU3F1 | 1 | 1p34.1 | Y | N |
| 2G10 | EST | AA772261 | — | 1 | 7 | Y | N |
| 3C64 | BAC | AC073094 | — | 1 | — | Y | N |
| 3D60 | BAC | AL036091 | — | 1 | 1q32.2-32.3 | Y | N |
| 3F16 | BAC | AL354950 | — | 1 | 10 | Y | Y |
| 3F72 | gene | NM022049 | G-protein–coupled receptor 88 | 1 | 1p21.3 | Y | Y |
| 3F82 | gene | XM006914 | Cold shock domain A | 1 | 12p13.1 | Y | N |
| *6E34 | gene | X69950 | WIT1 | 1 | 11p13 | Y | N |
A dash indicates data not available.
EST indicates expressed sequence tag; PAC, P1 artificial chromosome; BAC, bacterial artificial chromosomes.
Expression of this gene was analyzed previously in brain tumor cell lines (Costello et al19).