Multivariate Cox regression analyses for relapse
| . | All patients (n = 113) . | Low risk (n = 64) . | High risk (n = 49) . | |||
|---|---|---|---|---|---|---|
| RR (95% CI) . | P . | RR (95% CI) . | P . | RR (95% CI) . | P . | |
| Risk strata | 3.8 (1.6-8.8) | .0023 | ||||
| Patient age | 0.94 (0.91-0.98) | .003 | 0.94 (0.87-1.01) | .07 | 0.92 (0.86-0.97) | .0028 |
| Gender (male) | 1.5 (0.67-3.2) | .33 | 1.2 (0.22-6) | .87 | 1.4 (0.51-3.9) | .51 |
| Total cells (×108/kg) | 0.70 (0.38-1.3) | .26 | 0.2 (0.04-0.86) | .03 | 1.0 (0.43-2.3) | .99 |
| CD34+ (×106/kg) | 0.99 (0.71-1.4) | .94 | 0.79 (0.43-1.5) | .45 | 1.3 (0.83-2.1) | .24 |
| CD3+ (×106/kg) | 1 (0.97-1.1) | .44 | 1.0 (0.92-1.1) | .90 | 1.0 (0.96-3.9) | .31 |
| CD3−, CD4+, CD8−(×106/kg) | 1.8 (0.7-4.9) | .21 | 114 (3.6-3700) | .0074 | 0.67 (0.21-2.9) | .50 |
| . | All patients (n = 113) . | Low risk (n = 64) . | High risk (n = 49) . | |||
|---|---|---|---|---|---|---|
| RR (95% CI) . | P . | RR (95% CI) . | P . | RR (95% CI) . | P . | |
| Risk strata | 3.8 (1.6-8.8) | .0023 | ||||
| Patient age | 0.94 (0.91-0.98) | .003 | 0.94 (0.87-1.01) | .07 | 0.92 (0.86-0.97) | .0028 |
| Gender (male) | 1.5 (0.67-3.2) | .33 | 1.2 (0.22-6) | .87 | 1.4 (0.51-3.9) | .51 |
| Total cells (×108/kg) | 0.70 (0.38-1.3) | .26 | 0.2 (0.04-0.86) | .03 | 1.0 (0.43-2.3) | .99 |
| CD34+ (×106/kg) | 0.99 (0.71-1.4) | .94 | 0.79 (0.43-1.5) | .45 | 1.3 (0.83-2.1) | .24 |
| CD3+ (×106/kg) | 1 (0.97-1.1) | .44 | 1.0 (0.92-1.1) | .90 | 1.0 (0.96-3.9) | .31 |
| CD3−, CD4+, CD8−(×106/kg) | 1.8 (0.7-4.9) | .21 | 114 (3.6-3700) | .0074 | 0.67 (0.21-2.9) | .50 |
Separate analyses were performed for the entire group of patients (n = 113) and the subsets of low-isk (n = 64) and high-isk (n = 49) patients. All covariates listed were entered into the multivariate Cox model. Significant (P < .05) associations of covariates with EFS are in bold.