Relative contribution of necrosis and edema to focal cerebral ischemic injury
| Species . | FII . | Necrosis . | Edema . | Number . |
|---|---|---|---|---|
| Mouse | ||||
| Saline | 31 (27-32) | 26 (22-27) | 4.6 (1.4-5.8) | 6 |
| Pli (0.2 g) | 26 (24-28) | 22 (20-26) | 3.4 (0-5.9) | 6 |
| P | .01 | .025 | .33 | |
| Hamster | ||||
| Saline | 20 (9.9-38) | 16 (9.9-33) | 2.2 (0-5.6) | 6 |
| Pli (1 mg) | 7.1 (0.44-31) | 6.4 (0.44-26) | 0.34 (0-5.7) | 7 |
| P | .032 | .015 | .28 |
| Species . | FII . | Necrosis . | Edema . | Number . |
|---|---|---|---|---|
| Mouse | ||||
| Saline | 31 (27-32) | 26 (22-27) | 4.6 (1.4-5.8) | 6 |
| Pli (0.2 g) | 26 (24-28) | 22 (20-26) | 3.4 (0-5.9) | 6 |
| P | .01 | .025 | .33 | |
| Hamster | ||||
| Saline | 20 (9.9-38) | 16 (9.9-33) | 2.2 (0-5.6) | 6 |
| Pli (1 mg) | 7.1 (0.44-31) | 6.4 (0.44-26) | 0.34 (0-5.7) | 7 |
| P | .032 | .015 | .28 |
The data represent median (range) of volume, in μL3, of ischemic injury (FII), necrosis, or edema measured in groups of 6 or 7 animals at 24 hours.
FII indicates focal cerebral ischemic injury; for other abbreviations, see Table 2.