Distribution of methylation densities for CpG islands of 15 selected genes among 36 acute myeloid leukemia patients
| Gene . | Methylation density . | |||||
|---|---|---|---|---|---|---|
| Below 2% . | 2% to 9.9% . | At least 10% . | ||||
| No. . | % . | No. . | % . | No. . | % . | |
| Infrequently methylated genes | ||||||
| MLH1 | 36 | 100% | 0 | 0 | ||
| CACNA1G | 33 | 92% | 0 | 3 | 8% | |
| MINT2 | 34 | 94% | 0 | 2 | 6% | |
| MINT1 | 29 | 81% | 1 | 3% | 6 | 17% |
| THBS1 | 27 | 75% | 0 | 9 | 25% | |
| p16 | 30 | 83% | 0 | 6 | 17% | |
| MDR1 | 23 | 64% | 2 | 6% | 11 | 31% |
| PTC1A | 30 | 83% | 0 | 6 | 17% | |
| PTC1B | 32 | 89% | 0 | 4 | 11% | |
| p15 | 25 | 69% | 0 | 11 | 31% | |
| Frequently methylated genes | ||||||
| MyoD | 8 | 22% | 6 | 17% | 22 | 61% |
| SDC4 | 14 | 39% | 2 | 6% | 20 | 56% |
| GPR37 | 10 | 28% | 9 | 25% | 17 | 47% |
| PITX2 | 5 | 14% | 8 | 22% | 23 | 64% |
| ER (PCR) | 16 | 44% | 3 | 8% | 17 | 47% |
| Gene . | Methylation density . | |||||
|---|---|---|---|---|---|---|
| Below 2% . | 2% to 9.9% . | At least 10% . | ||||
| No. . | % . | No. . | % . | No. . | % . | |
| Infrequently methylated genes | ||||||
| MLH1 | 36 | 100% | 0 | 0 | ||
| CACNA1G | 33 | 92% | 0 | 3 | 8% | |
| MINT2 | 34 | 94% | 0 | 2 | 6% | |
| MINT1 | 29 | 81% | 1 | 3% | 6 | 17% |
| THBS1 | 27 | 75% | 0 | 9 | 25% | |
| p16 | 30 | 83% | 0 | 6 | 17% | |
| MDR1 | 23 | 64% | 2 | 6% | 11 | 31% |
| PTC1A | 30 | 83% | 0 | 6 | 17% | |
| PTC1B | 32 | 89% | 0 | 4 | 11% | |
| p15 | 25 | 69% | 0 | 11 | 31% | |
| Frequently methylated genes | ||||||
| MyoD | 8 | 22% | 6 | 17% | 22 | 61% |
| SDC4 | 14 | 39% | 2 | 6% | 20 | 56% |
| GPR37 | 10 | 28% | 9 | 25% | 17 | 47% |
| PITX2 | 5 | 14% | 8 | 22% | 23 | 64% |
| ER (PCR) | 16 | 44% | 3 | 8% | 17 | 47% |