Table 3. Hematologic data and iron... | American Society of Hematology

Table 3.

Hematologic data and iron parameters of hemochromatosis type 3 carriers with different TFR2 mutations

	Sex	Age	TS (%)	SF (μg/L)	Hb (g/L)	HFEmutations		TFR2 mutations
	Sex	Age	TS (%)	SF (μg/L)	Hb (g/L)	C282Y	H63D	Y250X	E60X	M172K
Family 1
V-2	M	68	36	97	166	−/−	−/−	+/−
V-9^3-150	M	70	74	310	159	−/−	−/−	+/−
VI-1	F	59	27	79	142			+/−
^3-151	F	17	38	47	155			+/−
^3-151,^3-152	M	13	25	58	132			+/−
^3-151	M	7	34	22	145			+/−
Family 3
V-4	F	78	ND	32	ND	−/−	−/−		+/−
VI-1	F	50	33	19	ND	−/−	−/−		+/−
VI-2	F	46	15	30	128	−/−	−/−		+/−
VI-6	M	34	26	183	156	−/−	−/−		+/−
VII-3	M	27	49	84	147	−/−	−/−		+/−
VII-4	M	19	35	33	ND	−/−	−/−		+/−
Family 4
I-2^3-153	F	72	39	180	112	−/−	+/−			+/−
III-1^3-153	M	18	40	75	132	−/−	−/−			+/−
III-2	M	16	30	44	140	−/−	−/−			+/−

	Sex	Age	TS (%)	SF (μg/L)	Hb (g/L)	HFEmutations		TFR2 mutations
	Sex	Age	TS (%)	SF (μg/L)	Hb (g/L)	C282Y	H63D	Y250X	E60X	M172K
Family 1
V-2	M	68	36	97	166	−/−	−/−	+/−
V-9^3-150	M	70	74	310	159	−/−	−/−	+/−
VI-1	F	59	27	79	142			+/−
^3-151	F	17	38	47	155			+/−
^3-151,^3-152	M	13	25	58	132			+/−
^3-151	M	7	34	22	145			+/−
Family 3
V-4	F	78	ND	32	ND	−/−	−/−		+/−
VI-1	F	50	33	19	ND	−/−	−/−		+/−
VI-2	F	46	15	30	128	−/−	−/−		+/−
VI-6	M	34	26	183	156	−/−	−/−		+/−
VII-3	M	27	49	84	147	−/−	−/−		+/−
VII-4	M	19	35	33	ND	−/−	−/−		+/−
Family 4
I-2^3-153	F	72	39	180	112	−/−	+/−			+/−
III-1^3-153	M	18	40	75	132	−/−	−/−			+/−
III-2	M	16	30	44	140	−/−	−/−			+/−

For abbreviations, see Table 2.

HCV chronic hepatis.

Children of patients VII-1 and VII-2.

δβ-thalassemia.

β-thalassemia trait.