Predicted amino acid sequences of the CDR3 loops of the BV5+ CD8+ PBMCs of patient T20
| Sample . | BV . | BJ . | CDR3 . | Frequency . | Length (aa) . |
|---|---|---|---|---|---|
| T20/M3 | 2 | 2S1 | PQTGDHEQ | 3/11 | 8 |
| T20/M3 | 2 | 2S3 | RGQTAQETQ | 5/11 | 9 |
| T20/M3 | 2 | 2S1 | RVGRANYNEQ | 1/11 | 10 |
| T20/M3 | 2 | 2S1 | RDHTGTGDNE | 1/11 | 10 |
| T20/M3 | 2 | 2S5 | RERDRETSGSR | 1/11 | 11 |
| T20/M12 | 2 | 1S1 | SGGTEA | 1/18 | 6 |
| T20/M12 | 2 | 2S3 | PTRSDTQ | 1/18 | 7 |
| T20/M12 | 2 | 1S1 | GETGGLGA | 1/18 | 8 |
| T20/M12 | 2 | 2S3 | RGQTAQETQ | 2/18 | 9 |
| T20/M12 | 2 | 2S3 | WIAERADTQ | 1/18 | 9 |
| T20/M12 | 2 | 2S1 | RGLASYNEQ | 1/18 | 9 |
| T20/M12 | 2 | 2S3 | GRGDSQETQ | 1/18 | 9 |
| T20/M12 | 2 | 1S3 | RVGTGDTEA | 1/18 | 9 |
| T20/M12 | 2 | 2S3 | SFTSGQETQ | 1/18 | 9 |
| T20/M12 | 2 | 2S3 | LPGLATTDTQ | 2/18 | 10 |
| T20/M12 | 2 | 2S6 | SGGMPGANVL | 1/18 | 10 |
| T20/M12 | 2 | 2S2 | RKRERGTGEL | 1/18 | 10 |
| T20/M12 | 2 | 2S3 | RGLAGGPGETQ | 1/18 | 11 |
| T20/M12 | 2 | 2S2 | REEGRRSTGEL | 1/18 | 11 |
| T20/M12 | 2 | 2S3 | TGLADLLRGGYEQ | 2/18 | 12 |
| T20/M0 | 5 | 1S6 | LGGRNSPLH | 11/13 | 9 |
| T20/M0 | 5 | 1S1 | LAGEGKGTEAF | 1/13 | 11 |
| T20/M0 | 5 | 1S6 | QQPWWQNSPLH | 1/13 | 11 |
| T20/M6 | 5 | 1S6 | LGGRNSPLH | 9/9 | 9 |
| T20/M12 | 5 | 1S1 | SRATEA | 1/18 | 6 |
| T20/M12 | 5 | 2S3 | PPPLYEQ | 1/18 | 7 |
| T20/M12 | 5 | 1S5 | FGWNQPQ | 1/18 | 7 |
| T20/M12 | 5 | 1S1 | SNWDTEA | 1/18 | 7 |
| T20/M12 | 5 | 2S3 | FGTSQETQ | 1/18 | 8 |
| T20/M12 | 5 | 1S1 | FLGFVTEA | 1/18 | 8 |
| T20/M12 | 5 | 2S3 | GNRAQETQ | 1/18 | 8 |
| T20/M12 | 5 | 2S3 | LWRAPSTQ | 1/18 | 8 |
| T20/M12 | 5 | 2S3 | FRGGADTQ | 1/18 | 8 |
| T20/M12 | 5 | 2S2 | SGGNTGEL | 1/18 | 8 |
| T20/M12 | 5 | 2S3 | HFPTAAYEQ | 1/18 | 9 |
| T20/M12 | 5 | 2S3 | ALASGPETL | 1/18 | 9 |
| T20/M12 | 5 | 2S3 | LYVDGSYEQ | 1/18 | 9 |
| T20/M12 | 5 | 2S3 | FWRGSTDTQ | 1/18 | 9 |
| T20/M12 | 5 | 2S3 | GRTAYTDTQ | 1/18 | 9 |
| T20/M12 | 5 | 1S1 | AARTSGDEQ | 1/18 | 9 |
| T20/M12 | 5 | 2S1 | RRTGTGYSEQ | 1/18 | 10 |
| T20/M12 | 5 | 1S2 | LGSTADSYGY | 1/18 | 10 |
| Sample . | BV . | BJ . | CDR3 . | Frequency . | Length (aa) . |
|---|---|---|---|---|---|
| T20/M3 | 2 | 2S1 | PQTGDHEQ | 3/11 | 8 |
| T20/M3 | 2 | 2S3 | RGQTAQETQ | 5/11 | 9 |
| T20/M3 | 2 | 2S1 | RVGRANYNEQ | 1/11 | 10 |
| T20/M3 | 2 | 2S1 | RDHTGTGDNE | 1/11 | 10 |
| T20/M3 | 2 | 2S5 | RERDRETSGSR | 1/11 | 11 |
| T20/M12 | 2 | 1S1 | SGGTEA | 1/18 | 6 |
| T20/M12 | 2 | 2S3 | PTRSDTQ | 1/18 | 7 |
| T20/M12 | 2 | 1S1 | GETGGLGA | 1/18 | 8 |
| T20/M12 | 2 | 2S3 | RGQTAQETQ | 2/18 | 9 |
| T20/M12 | 2 | 2S3 | WIAERADTQ | 1/18 | 9 |
| T20/M12 | 2 | 2S1 | RGLASYNEQ | 1/18 | 9 |
| T20/M12 | 2 | 2S3 | GRGDSQETQ | 1/18 | 9 |
| T20/M12 | 2 | 1S3 | RVGTGDTEA | 1/18 | 9 |
| T20/M12 | 2 | 2S3 | SFTSGQETQ | 1/18 | 9 |
| T20/M12 | 2 | 2S3 | LPGLATTDTQ | 2/18 | 10 |
| T20/M12 | 2 | 2S6 | SGGMPGANVL | 1/18 | 10 |
| T20/M12 | 2 | 2S2 | RKRERGTGEL | 1/18 | 10 |
| T20/M12 | 2 | 2S3 | RGLAGGPGETQ | 1/18 | 11 |
| T20/M12 | 2 | 2S2 | REEGRRSTGEL | 1/18 | 11 |
| T20/M12 | 2 | 2S3 | TGLADLLRGGYEQ | 2/18 | 12 |
| T20/M0 | 5 | 1S6 | LGGRNSPLH | 11/13 | 9 |
| T20/M0 | 5 | 1S1 | LAGEGKGTEAF | 1/13 | 11 |
| T20/M0 | 5 | 1S6 | QQPWWQNSPLH | 1/13 | 11 |
| T20/M6 | 5 | 1S6 | LGGRNSPLH | 9/9 | 9 |
| T20/M12 | 5 | 1S1 | SRATEA | 1/18 | 6 |
| T20/M12 | 5 | 2S3 | PPPLYEQ | 1/18 | 7 |
| T20/M12 | 5 | 1S5 | FGWNQPQ | 1/18 | 7 |
| T20/M12 | 5 | 1S1 | SNWDTEA | 1/18 | 7 |
| T20/M12 | 5 | 2S3 | FGTSQETQ | 1/18 | 8 |
| T20/M12 | 5 | 1S1 | FLGFVTEA | 1/18 | 8 |
| T20/M12 | 5 | 2S3 | GNRAQETQ | 1/18 | 8 |
| T20/M12 | 5 | 2S3 | LWRAPSTQ | 1/18 | 8 |
| T20/M12 | 5 | 2S3 | FRGGADTQ | 1/18 | 8 |
| T20/M12 | 5 | 2S2 | SGGNTGEL | 1/18 | 8 |
| T20/M12 | 5 | 2S3 | HFPTAAYEQ | 1/18 | 9 |
| T20/M12 | 5 | 2S3 | ALASGPETL | 1/18 | 9 |
| T20/M12 | 5 | 2S3 | LYVDGSYEQ | 1/18 | 9 |
| T20/M12 | 5 | 2S3 | FWRGSTDTQ | 1/18 | 9 |
| T20/M12 | 5 | 2S3 | GRTAYTDTQ | 1/18 | 9 |
| T20/M12 | 5 | 1S1 | AARTSGDEQ | 1/18 | 9 |
| T20/M12 | 5 | 2S1 | RRTGTGYSEQ | 1/18 | 10 |
| T20/M12 | 5 | 1S2 | LGSTADSYGY | 1/18 | 10 |
For the corresponding Immunoscope analysis, see Figure 3. Redundant sequences corresponding to identical DNA sequences and, thus, to clonal expansions, are in boldface.
aa indicates amino acid.