Genes similarly regulated by both KIM5 (pCD1+) and KIM6 (pCD1−) strains of Y pestis
| . | E colinonresponsive . | E coli responsive . | ||||
|---|---|---|---|---|---|---|
| Y pestis responsive . | Y pestisnonresponsive . | Y pestis responsive . | ||||
| E coliK12 | NC | NC | Up-regulated | Down-regulated | Up-regulated | Down-regulated |
| KIM5 | Up-regulated | Down-regulated | NC | NC | Up-regulated | Down-regulated |
| KIM6 | Up-regulated | Down-regulated | NC | NC | Up-regulated | Down-regulated |
| Receptors | ITGB2 | — | FCAR | FCER1G | TNFAIP6 | FCGR3A |
| IL8RA PTPRC | ||||||
| Chaperones | — | — | — | — | HSPCB | — |
| Transcription modulators | — | — | ETS2 | NACA | — | MNDA |
| Apoptosis regulators | — | — | — | — | GADD45B | — |
| Proteases | CTSD | — | TIMP1 | — | CPD | — |
| Protein kinases | — | — | — | GPRK6 | MAP2K3 | — |
| Other signal transducers | RALGDS ICAM3 LSP1 | RGS2 | EHD1 | PTPN6 TYROBP | MACS | HPCAL1 RGS14 |
| Membrane trafficking | — | — | — | — | RAB7 VATD | ATP6S1 |
| Oxidases | — | CYBA | — | — | — | — |
| Others | RPL18A ULK1 | — | EMD | LOC51669BB1 | HMOX1 H1F2 | DNM2 |
| HMG17 | KIAA1100 | |||||
| KIAA0370 | ||||||
| Gene expression pattern | LLHH | HHLL | LHLL | HLHH | LHHH | HLLL |
| . | E colinonresponsive . | E coli responsive . | ||||
|---|---|---|---|---|---|---|
| Y pestis responsive . | Y pestisnonresponsive . | Y pestis responsive . | ||||
| E coliK12 | NC | NC | Up-regulated | Down-regulated | Up-regulated | Down-regulated |
| KIM5 | Up-regulated | Down-regulated | NC | NC | Up-regulated | Down-regulated |
| KIM6 | Up-regulated | Down-regulated | NC | NC | Up-regulated | Down-regulated |
| Receptors | ITGB2 | — | FCAR | FCER1G | TNFAIP6 | FCGR3A |
| IL8RA PTPRC | ||||||
| Chaperones | — | — | — | — | HSPCB | — |
| Transcription modulators | — | — | ETS2 | NACA | — | MNDA |
| Apoptosis regulators | — | — | — | — | GADD45B | — |
| Proteases | CTSD | — | TIMP1 | — | CPD | — |
| Protein kinases | — | — | — | GPRK6 | MAP2K3 | — |
| Other signal transducers | RALGDS ICAM3 LSP1 | RGS2 | EHD1 | PTPN6 TYROBP | MACS | HPCAL1 RGS14 |
| Membrane trafficking | — | — | — | — | RAB7 VATD | ATP6S1 |
| Oxidases | — | CYBA | — | — | — | — |
| Others | RPL18A ULK1 | — | EMD | LOC51669BB1 | HMOX1 H1F2 | DNM2 |
| HMG17 | KIAA1100 | |||||
| KIAA0370 | ||||||
| Gene expression pattern | LLHH | HHLL | LHLL | HLHH | LHHH | HLLL |
For abbreviations, see Table 4 and Appendix A1.