Detection of retroviral vector-positive cells more than 6 months after transplantation of transduced FLCs into E13.5 MPS VII fetuses
| Organ . | PCR-positive cells, % . | |||
|---|---|---|---|---|
| Mouse 1 . | Mouse 2 . | Mouse 3 . | Mouse 4 . | |
| Blood | 0.1-1.0 | 0.01-0.1 | 0.01-0.1 | 0.01-0.1 |
| Brain | Negative | 0.01-0.1 | 1-10 | Negative |
| Liver | 0.01-0.1 | Negative | 0.1-1.0 | 0.01-0.1 |
| Spleen | 0.1-1.0 | Negative | Negative | Negative |
| Bone marrow | 0.01-0.1 | 0.01-0.1 | 0.01-0.1 | Negative |
| Organ . | PCR-positive cells, % . | |||
|---|---|---|---|---|
| Mouse 1 . | Mouse 2 . | Mouse 3 . | Mouse 4 . | |
| Blood | 0.1-1.0 | 0.01-0.1 | 0.01-0.1 | 0.01-0.1 |
| Brain | Negative | 0.01-0.1 | 1-10 | Negative |
| Liver | 0.01-0.1 | Negative | 0.1-1.0 | 0.01-0.1 |
| Spleen | 0.1-1.0 | Negative | Negative | Negative |
| Bone marrow | 0.01-0.1 | 0.01-0.1 | 0.01-0.1 | Negative |
PCR indicates polymerase chain reaction.