Clinical characteristics of 138 chronic myeloid leukemia patients according to early reverse transcriptase–polymerase chain reaction results after allogeneic stem cell transplantation
| . | Negative . | Low-level positive . | High-level positive . | P . |
|---|---|---|---|---|
| Sex, no. (%) | ||||
| Male | 30 (49) | 6 (43) | 38 (60) | NS |
| Female | 31 (51) | 8 (57) | 25 (40) | |
| Age, y*(range) | 33.5 | 35.5 | 33.9 | NS |
| (6.5-55.4) | (22.6-54.2) | (9.7-56.7) | ||
| Type of donor, no. (%) | ||||
| SIB | 36 (59) | 7 (50) | 24 (38) | .01 |
| URD | 25 (41) | 7 (50) | 39 (62) | |
| Interval from diagnosis to SCT, mo*(range) | 11 (4-73) | 15 (4-36) | 15 (3-64) | NS |
| Disease status at SCT, no. (%) | ||||
| Chronic phase | 51 (84) | 10 (71) | 52 (83) | NS |
| Accelerated phase | 10 (16) | 4 (29) | 11 (17) | |
| GVHD prophylaxis, no. (%) | ||||
| Non-TCD | 33 (54) | 6 (43) | 20 (32) | .02 |
| TCD | 28 (46) | 8 (57) | 43 (68) | |
| CMV seropositive, no. (%) | 26 (43) | 8 (57) | 27 (42) | NS |
| Acute GVHD after SCT, no. (%) | ||||
| 0-I | 23 (38) | 7 (50) | 33 (52) | |
| II | 32 (52) | 5 (36) | 27 (43) | NS |
| III-IV | 6 (10) | 2 (14) | 3 (5) |
| . | Negative . | Low-level positive . | High-level positive . | P . |
|---|---|---|---|---|
| Sex, no. (%) | ||||
| Male | 30 (49) | 6 (43) | 38 (60) | NS |
| Female | 31 (51) | 8 (57) | 25 (40) | |
| Age, y*(range) | 33.5 | 35.5 | 33.9 | NS |
| (6.5-55.4) | (22.6-54.2) | (9.7-56.7) | ||
| Type of donor, no. (%) | ||||
| SIB | 36 (59) | 7 (50) | 24 (38) | .01 |
| URD | 25 (41) | 7 (50) | 39 (62) | |
| Interval from diagnosis to SCT, mo*(range) | 11 (4-73) | 15 (4-36) | 15 (3-64) | NS |
| Disease status at SCT, no. (%) | ||||
| Chronic phase | 51 (84) | 10 (71) | 52 (83) | NS |
| Accelerated phase | 10 (16) | 4 (29) | 11 (17) | |
| GVHD prophylaxis, no. (%) | ||||
| Non-TCD | 33 (54) | 6 (43) | 20 (32) | .02 |
| TCD | 28 (46) | 8 (57) | 43 (68) | |
| CMV seropositive, no. (%) | 26 (43) | 8 (57) | 27 (42) | NS |
| Acute GVHD after SCT, no. (%) | ||||
| 0-I | 23 (38) | 7 (50) | 33 (52) | |
| II | 32 (52) | 5 (36) | 27 (43) | NS |
| III-IV | 6 (10) | 2 (14) | 3 (5) |
NS indicates not sufficient data; SIB, sibling donor; URD, unrelated donor; SCT, stem cell transplantation; GVHD, graft-versus-host disease; TCD, T-cell depletion; CMV, cytomegalovirus.
Median values.