Table 1. Binding affinity of human... | American Society of Hematology

Table 1.

Binding affinity of human GM-CSF receptors in M1 cells expressing human β_c and various α subunit constructs

Cell line	High affinity		Low affinity
Cell line	k_d(pM)^*	Sites^†	k_d (nM)	Sites
M1/α-1	0	0	2.2	22 415
M1/α-2	0	0	1.2	17 200
M1/β_c/α-1	10	3130	1.1	12 320
M1/β_c/α-2	50	3160	3.0	14 300
M1/β_c/GM5	10	4190	0.9	20 105
M1/β_c/term-3	66	2560	8.8	24 600
M1/β_c/term-1	56	3520	7.2	32 800

Cell line	High affinity		Low affinity
Cell line	k_d(pM)^*	Sites^†	k_d (nM)	Sites
M1/α-1	0	0	2.2	22 415
M1/α-2	0	0	1.2	17 200
M1/β_c/α-1	10	3130	1.1	12 320
M1/β_c/α-2	50	3160	3.0	14 300
M1/β_c/GM5	10	4190	0.9	20 105
M1/β_c/term-3	66	2560	8.8	24 600
M1/β_c/term-1	56	3520	7.2	32 800

Values are the means of duplicate determinations from a pool of 3 independently derived pools of retrovirally transduced cells.

Sites per cell.