Nucleotide substitutions detected in the FVgene of the proband
| Codon . | Nucleotide . | Amino acid . |
|---|---|---|
| 708 | ATT → ATC | I |
| 717 | AAC → AAT | N |
| 735 | GAA → GAG | E |
| 756 | AGT → GGT | S → G |
| 830 | AGA → AAA | R → K |
| 837 | CGT → CAT | R → H |
| 1 198 | CTC → CTT | L |
| Codon . | Nucleotide . | Amino acid . |
|---|---|---|
| 708 | ATT → ATC | I |
| 717 | AAC → AAT | N |
| 735 | GAA → GAG | E |
| 756 | AGT → GGT | S → G |
| 830 | AGA → AAA | R → K |
| 837 | CGT → CAT | R → H |
| 1 198 | CTC → CTT | L |
All polymorphisms were identified in exon 13. Codon numbering was done according to GenBank M16967. The polymorphism identified at codon 756 was detected in this study; all other polymorphisms were also identified by Shen et al.35