Parameters considered for the univariate and multivariable models
Patient data: |
Age* |
Karnofsky score† |
CMV serology† |
Disease data: |
WBC count at diagnosis (× 109/L)* |
Cytogenetics† |
BM blasts at BMT (%)* |
Disease stage at BMT† |
Time from diagnosis to BMT* |
Donor data: |
Age* |
CMV serology† |
Transplant data: |
Year of transplant* |
HLA matching† |
TBI applied† |
Ara-C or VP-16 added to TBI† |
Marrow cell dose* |
T-cell depletion† |
MTX + CSA included for GVH prophylaxis† |
ALG included in conditioning† |
Patient data: |
Age* |
Karnofsky score† |
CMV serology† |
Disease data: |
WBC count at diagnosis (× 109/L)* |
Cytogenetics† |
BM blasts at BMT (%)* |
Disease stage at BMT† |
Time from diagnosis to BMT* |
Donor data: |
Age* |
CMV serology† |
Transplant data: |
Year of transplant* |
HLA matching† |
TBI applied† |
Ara-C or VP-16 added to TBI† |
Marrow cell dose* |
T-cell depletion† |
MTX + CSA included for GVH prophylaxis† |
ALG included in conditioning† |
CMV indicates cytomegalovirus; TBI, total body irradiation; Ara-C, cytarabin; VP-16, etoposide; MTX + CSA, methotrexate + cyclosporin A; GVH, graft-versus-host; ALG, antilymphocyte globulin.
Continuous variables were treated as categorical in the univariate analysis, typically with the variables split at their medians.
Continuous variable.
Categorical variable.