Fetal liver cells from PDGFRβ null embryos can completely repopulate the peripheral blood compartment of lethally irradiated hosts
| Blood parameter . | Donor PDGFRβ genotype . | |||
|---|---|---|---|---|
| +/+ (n = 5) . | −/− (n = 5) . | |||
| Mean . | ± SD . | Mean . | ± SD . | |
| Hematocrit (%) | 38.60 | ± 3.10 | 37.50 | ± 10.20 |
| Erythrocytes (×1012/L) | 8.70 | ± 1.00 | 7.80 | ± 2.50 |
| Hemoglobin (g/dL) | 12.70 | ± 1.60 | 11.70 | ± 3.00 |
| MCV (fL) | 44.50 | ± 2.70 | 49.40 | ± 5.80 |
| MCHC (%) | 32.70 | ± 2.10 | 31.30 | ± 2.10 |
| WBC (×109/L) | 8.50 | ± 1.70 | 8.50 | ± 3.30 |
| PMN (×109/L) | 2.40 | ± 1.50 | 2.70 | ± 1.60 |
| Lymphocytes (×109/L) | 5.00 | ± 2.40 | 5.00 | ± 4.00 |
| Monocytes (×109/L) | 0.79 | ± 0.36 | 0.55 | ± 0.30 |
| Platelets (×109/L) | 939.00 | ± 65.00 | 1010.00 | ± 129.00 |
| Blood parameter . | Donor PDGFRβ genotype . | |||
|---|---|---|---|---|
| +/+ (n = 5) . | −/− (n = 5) . | |||
| Mean . | ± SD . | Mean . | ± SD . | |
| Hematocrit (%) | 38.60 | ± 3.10 | 37.50 | ± 10.20 |
| Erythrocytes (×1012/L) | 8.70 | ± 1.00 | 7.80 | ± 2.50 |
| Hemoglobin (g/dL) | 12.70 | ± 1.60 | 11.70 | ± 3.00 |
| MCV (fL) | 44.50 | ± 2.70 | 49.40 | ± 5.80 |
| MCHC (%) | 32.70 | ± 2.10 | 31.30 | ± 2.10 |
| WBC (×109/L) | 8.50 | ± 1.70 | 8.50 | ± 3.30 |
| PMN (×109/L) | 2.40 | ± 1.50 | 2.70 | ± 1.60 |
| Lymphocytes (×109/L) | 5.00 | ± 2.40 | 5.00 | ± 4.00 |
| Monocytes (×109/L) | 0.79 | ± 0.36 | 0.55 | ± 0.30 |
| Platelets (×109/L) | 939.00 | ± 65.00 | 1010.00 | ± 129.00 |
Peripheral blood parameters of hematopoietic chimeras were evaluated 14 to 18 weeks after transplantation. See Table 3 for abbreviations.