Table 2.

GENEHUNTER analysis of 35 DBA pedigrees

Chromosome 8p; HLOD scores of 35 DBA pedigrees at θ = 0.0
Penetrance
Locus
(from pter)
Genetic
distance
(cM)
Physical
distance
(Mb)
70%80%85%90%95%
HLOD (α)HLOD (α)HLOD (α)HLOD (α)HLOD (α)
D8S264 0.7 4.42 2.00  (0.47) 2.12  (0.46) 2.20  (0.44) 2.24  (0.43) 2.29  (0.41) 
D8S518 6.5 7.66 2.34  (0.48) 2.44  (0.46) 2.48  (0.45) 2.53  (0.43) 2.57  (0.41) 
D8S277 8.4 8.37 3.33  (0.56) 3.45  (0.53) 3.50  (0.52) 3.55  (0.50) 3.59  (0.48) 
D8S1819 10 8.77 3.29  (0.55) 3.41  (0.53) 3.47  (0.51) 3.52  (0.50) 3.57  (0.47) 
D8S439  8.77 3.23  (0.55) 3.34  (0.52) 3.40  (0.51) 3.45  (0.49) 3.50  (0.47) 
D8S1825 14.6 9.55 2.81  (0.52) 2.93  (0.50) 2.98  (0.50) 3.04  (0.47) 3.1   (0.45) 
D8S1130 14.8 11.04 2.79  (0.52) 2.91  (0.50) 2.97  (0.49) 3.03  (0.47) 3.1   (0.45) 
D8S1145 26.4 17.7 0.64  (0.36) 0.68  (0.35) 0.71  (0.35) 0.73  (0.34) 0.75  (0.33) 
Chromosome 8p; HLOD scores of 35 DBA pedigrees at θ = 0.0
Penetrance
Locus
(from pter)
Genetic
distance
(cM)
Physical
distance
(Mb)
70%80%85%90%95%
HLOD (α)HLOD (α)HLOD (α)HLOD (α)HLOD (α)
D8S264 0.7 4.42 2.00  (0.47) 2.12  (0.46) 2.20  (0.44) 2.24  (0.43) 2.29  (0.41) 
D8S518 6.5 7.66 2.34  (0.48) 2.44  (0.46) 2.48  (0.45) 2.53  (0.43) 2.57  (0.41) 
D8S277 8.4 8.37 3.33  (0.56) 3.45  (0.53) 3.50  (0.52) 3.55  (0.50) 3.59  (0.48) 
D8S1819 10 8.77 3.29  (0.55) 3.41  (0.53) 3.47  (0.51) 3.52  (0.50) 3.57  (0.47) 
D8S439  8.77 3.23  (0.55) 3.34  (0.52) 3.40  (0.51) 3.45  (0.49) 3.50  (0.47) 
D8S1825 14.6 9.55 2.81  (0.52) 2.93  (0.50) 2.98  (0.50) 3.04  (0.47) 3.1   (0.45) 
D8S1130 14.8 11.04 2.79  (0.52) 2.91  (0.50) 2.97  (0.49) 3.03  (0.47) 3.1   (0.45) 
D8S1145 26.4 17.7 0.64  (0.36) 0.68  (0.35) 0.71  (0.35) 0.73  (0.34) 0.75  (0.33) 
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