Comparison of prognostic models including β2m ≥ 2.5 mg/L and another factor3-150
| Factor in addition to β2m ≥ 2.5 mg/L . | Decrease in −2 × logarithm (likelihood) . | ||||
|---|---|---|---|---|---|
| (n = 110) . | (n = 108) . | (n = 102) . | (n = 100) . | (n = 90) . | |
| None | 18.465 | 18.269 | 15.384 | 15.202 | 10.950 |
| Chr 13 deletion | 35.643 | 35.620 | 33.767 | 34.768 | 27.736 |
| Age ≥ 60 y | 22.842 | 22.782 | 18.300 | 18.169 | 13.303 |
| Creatinine > 12 mg/L | 22.076 | 21.818 | 18.953 | 18.707 | 14.301 |
| Isotype IgA | 32.148 | 30.260 | 24.214 | ||
| λ light chain | 24.503 | 20.232 | 15.646 | ||
| CRP ≥ 6 mg/L | 21.477 | 21.262 | 17.734 | ||
| LDH > 230 UI/L | 17.313 | ||||
| Sample | Any patient | Except non-excreting MM | Except CRP missing | Except non-excreting MM and CRP missing | Except non-excreting MM, CRP and LDH missing |
| Factor in addition to β2m ≥ 2.5 mg/L . | Decrease in −2 × logarithm (likelihood) . | ||||
|---|---|---|---|---|---|
| (n = 110) . | (n = 108) . | (n = 102) . | (n = 100) . | (n = 90) . | |
| None | 18.465 | 18.269 | 15.384 | 15.202 | 10.950 |
| Chr 13 deletion | 35.643 | 35.620 | 33.767 | 34.768 | 27.736 |
| Age ≥ 60 y | 22.842 | 22.782 | 18.300 | 18.169 | 13.303 |
| Creatinine > 12 mg/L | 22.076 | 21.818 | 18.953 | 18.707 | 14.301 |
| Isotype IgA | 32.148 | 30.260 | 24.214 | ||
| λ light chain | 24.503 | 20.232 | 15.646 | ||
| CRP ≥ 6 mg/L | 21.477 | 21.262 | 17.734 | ||
| LDH > 230 UI/L | 17.313 | ||||
| Sample | Any patient | Except non-excreting MM | Except CRP missing | Except non-excreting MM and CRP missing | Except non-excreting MM, CRP and LDH missing |
Only relevant combinations are presented. The higher the decrease in −2 × logarithm (likelihood), which follows a chi-square distribution with 2 degrees of freedom (except in line “non” with one degree of freedom), the more powerful is the corresponding model.