Table 2. Prognostic factors at... | American Society of Hematology

Table 2.

Prognostic factors at diagnosis, univariate analysis

		N^*	Overall survival^†		Progression-free survival		N^2-153	Survival after progression
		N^*	RR^†	P^‡	RR	P	N^2-153	RR	P
Δ13	Abn/N	110	3.3	< .0001	2.2	.0005	79	2.4	.0018
β₂m (mg/L)	≥ 2.5/< 2.5	110	4.6	.0001	2.3	.0017	79	2.6	.0176
	≥ 3.0/< 3.0	110	2.2	.0100	1.8	.0164	79	1.4	.2255
Conv karyotype	Abn/N	60	3.4	.0005	2.4	.0048	46	2.0	.0530
LDH (UI/L)	> 230/≤ 230	98	2.6	.0013	1.5	.0941	77	2.1	.0120
Stage	PCL/I-II	110	5.7	.0015	3.5	.0069	79	4.5	.0084
	III/I-II		1.8		1.8			1.1
Type of light chain	λ/K	108	2.2	.0048	1.1	.5978	77	2.2	.0052
Age (y)	≥ 60/< 60	110	2.1	.0126	1.4	.2023	79	1.8	.0439
Hemoglobin (g/dL)	< 10/≥ 10	110	2.0	.0131	1.4	.1452	79	1.6	.1252
CRP (mg/L)	> 2.5/≤ 2.5	102	2.1	.0187	1.4	.1508	73	1.9	.0513
	≥ 6.0/< 6.0	102	1.9	.0323	1.2	.4230	73	2.0	.0190
Isotype	IgA yes/no	108	1.9	.0381	1.6	.0731	77	1.9	.0384
	IgG no/yes	108	1.6	.0753	1.8	.0088	77	1.3	.4174
Creatinine (mg/L)	> 10/≤ 10	110	1.7	.0597	1.3	.2646	79	1.7	.0489
Plasmacytosis (%)	> 25/≤ 25	108	1.5	.1542	1.7	.0327	77	1.2	.5119
	> 33/≤ 33	108	1.4	.2674	1.6	.0520	77	1.2	.5633
Albumin (g/L)	≤ 35/> 35	108	1.5	.1725	1.1	.7723	77	1.6	.1073

		N^*	Overall survival^†		Progression-free survival		N^2-153	Survival after progression
		N^*	RR^†	P^‡	RR	P	N^2-153	RR	P
Δ13	Abn/N	110	3.3	< .0001	2.2	.0005	79	2.4	.0018
β₂m (mg/L)	≥ 2.5/< 2.5	110	4.6	.0001	2.3	.0017	79	2.6	.0176
	≥ 3.0/< 3.0	110	2.2	.0100	1.8	.0164	79	1.4	.2255
Conv karyotype	Abn/N	60	3.4	.0005	2.4	.0048	46	2.0	.0530
LDH (UI/L)	> 230/≤ 230	98	2.6	.0013	1.5	.0941	77	2.1	.0120
Stage	PCL/I-II	110	5.7	.0015	3.5	.0069	79	4.5	.0084
	III/I-II		1.8		1.8			1.1
Type of light chain	λ/K	108	2.2	.0048	1.1	.5978	77	2.2	.0052
Age (y)	≥ 60/< 60	110	2.1	.0126	1.4	.2023	79	1.8	.0439
Hemoglobin (g/dL)	< 10/≥ 10	110	2.0	.0131	1.4	.1452	79	1.6	.1252
CRP (mg/L)	> 2.5/≤ 2.5	102	2.1	.0187	1.4	.1508	73	1.9	.0513
	≥ 6.0/< 6.0	102	1.9	.0323	1.2	.4230	73	2.0	.0190
Isotype	IgA yes/no	108	1.9	.0381	1.6	.0731	77	1.9	.0384
	IgG no/yes	108	1.6	.0753	1.8	.0088	77	1.3	.4174
Creatinine (mg/L)	> 10/≤ 10	110	1.7	.0597	1.3	.2646	79	1.7	.0489
Plasmacytosis (%)	> 25/≤ 25	108	1.5	.1542	1.7	.0327	77	1.2	.5119
	> 33/≤ 33	108	1.4	.2674	1.6	.0520	77	1.2	.5633
Albumin (g/L)	≤ 35/> 35	108	1.5	.1725	1.1	.7723	77	1.6	.1073

Number of patients involved in overall survival and progression-free survival analyses.

Relative risk of event.

Significance level.

Number of patients involved in survival after progression analysis.