Table 1.

Patient and treatment characteristics (n = 110, except where indicated)

Parameter at diagnosisNo. of patients%
Age ≥ 60 y 33 30  
Stage III 64 58 
PCL 5  
B substage (n = 104) 11 11  
IgA isotype (n = 108) 23 21  
λ light chain (n = 108) 36 33 
β2m ≥ 2.5 mg/L 79 71  
CRP ≥ 6 mg/L (n = 102) 43 42  
Bone marrow plasmacytosis > 25% (n = 108) 74 69  
Albumin ≤ 35 g/L (n = 108) 30 28  
Type of HDT   
 HDM 140 alone 5  
 1 autotransplant 62 56  
 Tandem autotransplants 20 18 
 1 HDT at diagnosis + 1 autotransplant at first relapse 21 19  
 Other type* 
Parameter at diagnosisNo. of patients%
Age ≥ 60 y 33 30  
Stage III 64 58 
PCL 5  
B substage (n = 104) 11 11  
IgA isotype (n = 108) 23 21  
λ light chain (n = 108) 36 33 
β2m ≥ 2.5 mg/L 79 71  
CRP ≥ 6 mg/L (n = 102) 43 42  
Bone marrow plasmacytosis > 25% (n = 108) 74 69  
Albumin ≤ 35 g/L (n = 108) 30 28  
Type of HDT   
 HDM 140 alone 5  
 1 autotransplant 62 56  
 Tandem autotransplants 20 18 
 1 HDT at diagnosis + 1 autotransplant at first relapse 21 19  
 Other type* 

PCL indicates primary plasma cell leukemia; HDT, high-dose therapy; HDM 140, high-dose melphalan 140 mg/m2.

*

One allogeneic bone marrow transplant and one autotransplant followed by an allogeneic transplant.

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