Summary of management of different types and subtypes of von Willebrand disease
| Type . | Treatment of choice . | Alternative or adjunctive therapy . |
|---|---|---|
| 1 | Desmopressin | Antifibrinolytic amino acids |
| 2A | Factor VIII-vWF concentrates | As above |
| 2B | Factor VIII-vWF concentrates | As above |
| 2M | Factor VIII-vWF concentrates | As above |
| 2N | Factor VIII-vWF concentrates | As above |
| 3 | Factor VIII-vWF concentrates | Antifibrinolytic amino acids, platelet concentrates |
| 3, complicated by alloantibodies | Recombinant factor VIII | Recombinant activated factor VII |
| Type . | Treatment of choice . | Alternative or adjunctive therapy . |
|---|---|---|
| 1 | Desmopressin | Antifibrinolytic amino acids |
| 2A | Factor VIII-vWF concentrates | As above |
| 2B | Factor VIII-vWF concentrates | As above |
| 2M | Factor VIII-vWF concentrates | As above |
| 2N | Factor VIII-vWF concentrates | As above |
| 3 | Factor VIII-vWF concentrates | Antifibrinolytic amino acids, platelet concentrates |
| 3, complicated by alloantibodies | Recombinant factor VIII | Recombinant activated factor VII |