Current classification of von Willebrand disease
| Type . | Description . |
|---|---|
| 1 | Partial quantitative deficiency of vWF |
| 2 | Qualitative deficiency of vWF |
| 2A | Decreased platelet-dependent vWF function, with lack of high molecular weight multimers (HMWM) |
| 2B | Increased vWF platelet-dependent vWF function, with lack of HMWM |
| 2M | Decreased platelet-dependent vWF function, with normal multimeric structure |
| 2N | Decreased vWF affinity for factor VIII |
| 3 | Complete deficiency of vWF |
| Type . | Description . |
|---|---|
| 1 | Partial quantitative deficiency of vWF |
| 2 | Qualitative deficiency of vWF |
| 2A | Decreased platelet-dependent vWF function, with lack of high molecular weight multimers (HMWM) |
| 2B | Increased vWF platelet-dependent vWF function, with lack of HMWM |
| 2M | Decreased platelet-dependent vWF function, with normal multimeric structure |
| 2N | Decreased vWF affinity for factor VIII |
| 3 | Complete deficiency of vWF |