Table 4. Serum hepatocyte growth factor... | American Society of Hematology

Table 4.

Serum hepatocyte growth factor levels in 106 patients with Hodgkin disease at diagnosis according to patient clinical and laboratory features

Patients	Serum HGF, pg/mL
Features	n	Mean ± SEM	Median	Range	P^4-150
Sex
Male	67	1374 ± 114	1179	350 -4925	.5
Female	39	1453 ± 156	1350	338 -5800
Age
≥40 y	37	1414 ± 149	1210	352 -4925	.8
<40 yr	69	1397 ± 117	1190	338 -5800
Stages
I-II	60	1259 ± 102	1068	350 -4190	.1
III-IV	46	1591 ± 161	1293	338 -5800
Stage A	50	1032 ± 88	874	338 -3186	<.0001
Stage B	56	1734 ± 141	1623	350 -5800
Bulky	33	1344 ± 150	1420	401 -4190	.1
Nonbulky	73	1344 ± 114	1150	338 -5800
Histological subtype
LR + NS I	53	1282 ± 130	1150	395 -5800	.8
NS II + MC + LD	40	1282 ± 128	1150	350 -4190
Hb, g/L
≥100.5	86	1293 ± 93	1046	338 -4925	.007
<100.5	19	1898 ± 267	1559	400 -5800
Albumin, g/L
≥40	80	1300 ± 97	1108	350 -4925	.09
<40	16	1801 ± 325	1500	400 -5800
ESR
Elevated	75	1586 ± 117	1420	338 -5800	.0002
Nonelevated	25	841 ± 74	730	352 -1700

Patients	Serum HGF, pg/mL
Features	n	Mean ± SEM	Median	Range	P^4-150
Sex
Male	67	1374 ± 114	1179	350 -4925	.5
Female	39	1453 ± 156	1350	338 -5800
Age
≥40 y	37	1414 ± 149	1210	352 -4925	.8
<40 yr	69	1397 ± 117	1190	338 -5800
Stages
I-II	60	1259 ± 102	1068	350 -4190	.1
III-IV	46	1591 ± 161	1293	338 -5800
Stage A	50	1032 ± 88	874	338 -3186	<.0001
Stage B	56	1734 ± 141	1623	350 -5800
Bulky	33	1344 ± 150	1420	401 -4190	.1
Nonbulky	73	1344 ± 114	1150	338 -5800
Histological subtype
LR + NS I	53	1282 ± 130	1150	395 -5800	.8
NS II + MC + LD	40	1282 ± 128	1150	350 -4190
Hb, g/L
≥100.5	86	1293 ± 93	1046	338 -4925	.007
<100.5	19	1898 ± 267	1559	400 -5800
Albumin, g/L
≥40	80	1300 ± 97	1108	350 -4925	.09
<40	16	1801 ± 325	1500	400 -5800
ESR
Elevated	75	1586 ± 117	1420	338 -5800	.0002
Nonelevated	25	841 ± 74	730	352 -1700

In Stage B, low Hb levels and elevated ESR are associated with higher serum HGF levels.

HGF indicates hepatocyte growth factor; Hb, hemoglobin; ESR, erythrocyte sedimentation ratio; see Table 1 for other abbreviations.

P value is based on the univariate analysis performed by the Mann-Whitney test.